Active Ingredient: Etanercept
Treatment of adults with severe non-radiographic axial spondyloarthritis with objective signs of inflammation as indicated by elevated C-reactive protein (CRP) and/or magnetic resonance imaging (MRI) evidence, who have had an inadequate response to nonsteroidal anti-inflammatory drugs (NSAIDs).
For this indication, competent medicine agencies globally authorize below treatments:
For:
Regimen A: Oral, 25 milligrams etanercept, 2 times weekly.
Regimen B: Oral, 50 milligrams etanercept, once weekly.
25 mg etanercept administered twice weekly is the recommended dose. Alternatively, 50 mg administered once weekly has been shown to be safe and effective.
Available data suggest that a clinical response is usually achieved within 12 weeks of treatment. Continued therapy should be carefully reconsidered in a patient not responding within this time period.
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