Active Ingredient: Human hepatitis B immunoglobulin
For this indication, competent medicine agencies globally authorize below treatments:
For:
Intravenous
30 - 100 [iU] per kg of body weight
From 30 To 100 [iU] per kg of body weight once every day
Prevention of hepatitis B in the newborn, of a hepatitis B virus carrier-mother, at birth or as soon as possible after birth: 30-100 IU (0.6-2 ml)/kg. The hepatitis B immunoglobulin administration may be repeated until seroconversion following vaccination.
Clinical experience in newborns of hepatitis B virus carrier mothers has shown, that human hepatitis B immunoglobulin solution intravenously used at an infusion rate of 2 ml in-between 5 to 15 minutes has been well tolerated.
For:
Intravenous
500 - 500 [iU]
From 500 To 500 [iU] once every day
Prevention of hepatitis B in case of accidental exposure in non-immunised subjects:
At least 500 IU (10 ml), depending on the intensity of exposure, as soon as possible after exposure, and preferably within 24-72 hours.
Human hepatitis B immunoglobulin solution should be infused intravenously at an initial rate of 0.1 ml/kg/hr for 10 minutes. In case of adverse reaction, either the rate of administration must be reduced or the infusion stopped. If well tolerated, the rate of administration may gradually be increased to a maximum of 1 ml/kg/hr.
For:
Intravenous
8 - 500 [iU]
From 8 To 500 [iU] once every day
Immunoprophylaxis of hepatitis B in haemodialysed patients: 8-12 IU (0.16-0.24 ml)/kg with a maximum of 500 IU (10 ml), every 2 months until seroconversion following vaccination.
Human hepatitis B immunoglobulin solution should be infused intravenously at an initial rate of 0.1 ml/kg/hr for 10 minutes. In case of adverse reaction, either the rate of administration must be reduced or the infusion stopped. If well tolerated, the rate of administration may gradually be increased to a maximum of 1 ml/kg/hr.
Liability Disclaimer : RxReasoner has utilized reasonable care in providing content and services that are accurate, complete and up to date. However, RxReasoner does not accept any responsibility or liability about it. The content and services of RxReasoner are for informational purposes only and they are not intended to be a substitute for the knowledge, expertise, skill, and judgment of physicians, pharmacists, nurses, or other healthcare professionals involved in patient care. RxReasoner offers no medical advice. Users are responsible for the use of the provided content. A shown indication or treatment should not be construed to indicate that the medication is safe, appropriate, or effective in any given patient or under any particular circumstances. The absence of an indication or treatment should not roule out the existence of other appropriate medications. Always seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition or medicament. RxReasoner is not liable for any damages allegedly sustained arising out of the use of its content and services.
