Acute gouty arthritis

Active Ingredient: Etoricoxib

Indication for Etoricoxib

Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)

Therapeutic intent: Curative procedure

Etoricoxib is indicated in adults and adolescents 16 years of age and older for the symptomatic relief of pain and signs of inflammation associated with acute gouty arthritis.

For this indication, competent medicine agencies globally authorize below treatments:

120 mg once daily

For:

Dosage regimens

In case that patient age in years is ≥ 16, oral, 120 milligrams etoricoxib, once daily.

Detailed description

For acute pain conditions, etoricoxib should be used only for the acute symptomatic period.

The recommended dose is 120 mg once daily. In clinical trials for acute gouty arthritis, etoricoxib was given for 8 days.

Active ingredient

Etoricoxib
Etoricoxib is an oral, selective cyclo-oxygenase-2 (COX-2) inhibitor within the clinical dose range. Cyclooxygenase is responsible for generation of prostaglandins. Two isoforms, COX-1 and COX-2, have been identified. COX-2 is the isoform of the enzyme that has been shown to be induced by pro-inflammatory stimuli and has been postulated to be primarily responsible for the synthesis of prostanoid mediators of pain, inflammation, and fever. COX-2 is also involved in ovulation, implantation and closure of the ductus arteriosus, regulation of renal function, and central nervous system functions (fever induction, pain perception and cognitive function). It may also play a role in ulcer healing. COX-2 has been identified in tissue around gastric ulcers in man but its relevance to ulcer healing has not been established. Read more about Etoricoxib

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Summary of Product Characteristics (SPC) 2022: ARCOXIA Film-coated tablet

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