Active Ingredient: Chloroprocaine
For this indication, competent medicine agencies globally authorize below treatments:
For:
Regimen A: Intraspinal, 40 milligrams chloroprocaine, one dose.
Regimen B: Intraspinal, 50 milligrams chloroprocaine, one dose.
Posology must be established on an individual basis in accordance with the characteristics of the specific case. When determining the dose, take into consideration the patient’s physical condition and the concomitant administration of other medicinal products.
The duration of action is dose-dependent.
The indications relating to recommended doses are valid in adults of average height and weight (approximately 70 kg) for obtaining an effective block with one single administration. There are wide individual variations with regard to extent and duration of action. The experience of the anaesthetist and knowledge of the patient’s general condition are essential for establishing the dose.
With regard to posology the following guidelines are applied.
Extension of sensory blockade required T10:
| ml | mg | Average duration of action (minutes) |
|---|---|---|
| 4 | 40 | 80 |
| 5 | 50 | 100 |
The maximum recommended dose is 50mg (=5ml) of chloroprocaine hydrochloride.
It is advisable to reduce the dose in patients in a compromised general condition.
In addition, in patients with established concomitant disorders (e.g. vascular occlusion, arteriosclerosis, diabetic polyneuropathy) a reduced dose is indicated.
For intrathecal use.
Inject the solution via intrathecal route into the intervertebral space L2/L3, L3/L4 and L4/L5.
Slowly inject the entire dose and check the patient’s vital functions extremely carefully maintaining continuous verbal contact.
For single use.
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