Secondary or acute narrow angle glaucoma

Active Ingredient: Acetazolamide

Indication for Acetazolamide

Population group: only adults (18 years old or older)

Acetazolamide is an enzyme inhibitor which acts specifically on carbonic anhydrase. Acetazolamide is useful in glaucoma (chronic simple (open angle) glaucoma, secondary glaucoma and perioperatively in acute angle closure glaucoma where delay of surgery is desired in order to lower intraocular pressure) because it acts on inflow, decreasing the amount of aqueous secretion.

For this indication, competent medicine agencies globally authorize below treatments:

250mg/4h or 12 hours

Route of admnistration

Oral

Defined daily dose

500 - 1,500 mg

Dosage regimen

From 83.333 To 250 mg 6 time(s) per day every day for 2 day(s)

Detailed description

Preoperatively, may be administered 250mg/4h or 12 hours depending on the case, for a short time.

500 mg once and then 125-500 mg/4h

Route of admnistration

Oral

Defined daily dose

750 - 3,000 mg

Dosage regimen

From 125 To 500 mg 6 time(s) per day every day for 3 day(s)

Loading dose

500 mg

Detailed description

Preoperatively, in some severe cases may be administered 500 mg once and then 125-500 mg/4h depending on the response.

250-1000mg per 24 hours

Route of admnistration

Intravenous

Defined daily dose

250 - 1,000 mg

Dosage regimen

From 62.5 To 250 mg 4 time(s) per day every day

Detailed description

250-1000mg per 24 hours, usually in divided doses for amounts over 250mg daily.

Active ingredient

Acetazolamide

Acetazolamide is an enzyme inhibitor which acts specifically on carbonic anhydrase. By inhibiting the reaction catalysed by this enzyme in the renal tubules, acetazolamide increases the excretion of bicarbonate and of cations, chiefly sodium and potassium, and so promotes alkaline diuresis. By inhibiting carbonic anhydrase in the eye acetazolamide decreases intra-ocular pressure and is therefore useful in the treatment of glaucoma.

Read more about Acetazolamide

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