Active Ingredient: Gadopentetate dimeglumine
For contrast enhancement in direct magnetic resonance arthrography.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Intra-articular, between 25 milliliters gadopentetate dimeglumine and 50 milliliters gadopentetate dimeglumine, one dose.
The recommendations for the use of gadopentetic acid 2 mmol/l apply to a field strength between 0.2 Tesla and 1.5 Tesla.
Intraarticular administrations of contrast agents are to be given with the patient lying or sitting. After the end of the injection, the patient should be kept under supervision for at least half an hour.
The lowest dose that provides sufficient enhancement for diagnostic purposes should be used.
In general, for all joints the administration of up to 20 ml (knee joint up to 50 ml) gadopentetic acid 2 mmol/l is sufficient for good opacification and to answer all the relevant clinical questions. A volume leading to a slight distension of the joint capsule should be injected. Only so much contrast medium should be injected until discrete resistance is felt and/or the patient experiences a mild feeling of pressure.
Guidelines on volumes to be administered:
| Joint | Volume required |
|---|---|
| Knee | 25-50 ml |
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