Active Ingredient: Tetrabenazine
Tetrabenazine is indicated for the treatment of moderate to severe tardive dyskinesia, which is disabling and/or socially embarrassing. The condition should be persistent despite withdrawal of antipsychotic therapy, or in cases where withdrawal of antipsychotic medication is not a realistic option; also where the condition persists despite reduction in dosage of antipsychotic medication or switching to atypical antipsychotic medication.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Oral, 12.5 milligrams tetrabenazine, once daily.
Recommended starting dose of 12.5 mg a day subsequently titrated according to response. Medication should be discontinued if there is no clear benefit or if the side-effects cannot be tolerated.
For any indication, if adverse events such as akathisia, restlessness, parkinsonism, depression, insomnia, anxiety, or intolerable sedation occur, titration should be stopped and the dose should be reduced.
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