Active Ingredient: Cenegermin
Treatment of moderate (persistent epithelial defect) or severe (corneal ulcer) neurotrophic keratitis in adults.
For this indication, competent medicine agencies globally authorize below treatments:
Ophthalmic
6 - 6 {drops}
From 1 To 1 {drops} 6 time(s) per day every day for 56 day(s)
The recommended dose is one drop of cenegermin in the conjunctival sac of the affected eye(s), 6 times a day at 2 hourly intervals, starting from the morning and within 12 hours. Treatment should be continued for eight weeks.
Patients with an eye infection should be treated before starting therapy with cenegermin.
If a dose is missed, treatment should be continued as normal, at the next scheduled administration. The missed dose can be administered later, within the 12 hours shelf-life of the daily vial. Patients should be advised not to instil more than one drop in the affected eye(s) during any administration.
Patients should be instructed to wash their hands before use.
Cenegermin should only be administered using the associated delivery system (vial adapter and pipettes), according to the instructions given. An individual pipette should be used per application.
If more than one topical ophthalmic product is being used, the eye drops must be administered at least 15 minutes apart, to avoid diluting the other product. If eye ointment, gel or other viscous eye drops are used, they should be administered 15 minutes following cenegermin treatment.
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