Active Ingredient: Encorafenib
Encorafenib in combination with binimetinib is indicated for the treatment of adult patients with unresectable or metastatic melanoma with a BRAF V600 mutation.
For this indication, competent medicine agencies globally authorize below treatments:
For:
Oral, 450 milligrams encorafenib, once daily.
The recommended dose of encorafenib is 450 mg once daily, when used in combination with binimetinib.
Treatment should continue until the patient no longer derives benefit or the development of unacceptable toxicity.
If a dose of encorafenib is missed, the patient should only take the missed dose if it is more than 12 hours until the next scheduled dose.
In case of vomiting after administration of encorafenib, the patient should not take an additional dose and should take the next scheduled dose.
They may be taken with or without food. The concomitant administration of encorafenib with grapefruit juice should be avoided.
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