This brand name is authorized in Nigeria.
The drug BIOTONIC PLUS contains a combination of these active pharmaceutical ingredients (APIs):
1
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UNII
UVP74NG1C5 - FERRIC AMMONIUM CITRATE
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2
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935E97BOY8 - FOLIC ACID
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Folic acid is a member of the vitamin B group which is reduced in the body to tetrahydrofolate, a co-enzyme active in several metabolic processes and produces a haemopoietic response in nutritional megaloblastic anaemias. Folic acid is rapidly absorbed and widely distributed in body tissues. |
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3
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P6YC3EG204 - CYANOCOBALAMIN
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Hydroxocobalamin is used in the treatment and prevention of Vitamin B12 deficiency. For adults, the daily requirement of Vitamin B12 is probably about 1 to 2 micrograms and this amount is present in most normal diets. However, Vitamin B12 only occurs in animal products, not in vegetables, and therefore strict vegetarian or vegan diets that exclude dairy products may provide an inadequate amount, although a deficiency may not be apparent for many years. |
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4
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PQ6CK8PD0R - ASCORBIC ACID
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Ascorbic acid, coupled with dehydroascorbic acid to which it is reversibly oxidised, has a variety of functions in cellular oxidation processes. Ascorbic acid is required in several important hydroxylations, including the conversion of proline to hydroxyproline and appears to have an important role in metal ion metabolism, including the gastrointestinal absorption of iron and its transport between plasma and storage organs. |
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5
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X66NSO3N35 - THIAMINE
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Thiamine pyrophosphate (TPP), the coenzymatic form of thiamine, is involved in two main types of metabolic reactions: decarboxylation of α-ketoacids (e.g. pyruvate, α-ketoglutarate and branched-chain keto acids) and transketolation (e.g. among hexose and pentose phosphates). Therefore, the principal physiological role of thiamine is as a coenzyme in carbohydrate metabolism, where TPP is required for several stages in the breakdown of glucose to provide energy. |
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6
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TLM2976OFR - RIBOFLAVIN
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Riboflavine is phosphorylated to flavine mononucleotide and flavine adenine dinucleotide which act as co-enzymes in the respiratory chain and in oxidative phosphorylation. Riboflavine deficiency presents with ocular symptoms, as well as lesions on the lips and at angles of the mouth. |
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7
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KV2JZ1BI6Z - PYRIDOXINE
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Pyridoxine hydrochloride is Vitamin B6. It is converted to pyridoxal phosphate which is the co-enzyme for a variety of metabolic transformations. It is essential for human nutrition. |
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8
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25X51I8RD4 - NIACINAMIDE
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9
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789U1901C5 - COPPER
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Copper is a mineral that is found throughout the body. Copper helps the body absorb iron. It is also important for nerve function, bone growth, and to help your body use sugar. It also helps form collagen, a key part of bones and connective tissue. Copper may also act as an antioxidant, reducing free radicals that can damage cells and DNA. |
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This drug has been approved in Nigeria as follows:
Identifier | Form | Presentation | Description | Approval |
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A4-2431 | Syrup | Biotonic Plus Syrup SYRUP 100 mg; 1.5 mg; 15 mcg; 75 mg; 61.8 mg 100ml, 200ml & 1000ml | 2 RNW-PP-306668 BIOTONIC PLUS SYRUP Ferric Ammonium Citrate Folic Acid Vitamin B1 Vitamin B2 (Riboflavin Phosphate) Vitamin B6 Vitamin B12 (Cyanocobalamin) Zinc Sulphate Copper Nicotinamide CETIRIZINE HCL 1.5MG, AMMONIUM CHLORIDE 45MG, SODIUM CITRATE 22MG, EPHEDRINE HCL 3MG, MENTHOL 2MG/5ML A4-2431 Drugs Nigerian Products 100ml,200ml&1000ml Over The Counter (OTC) 1/17/2023 BIORAJ PHARMACEUTICALS LIMITED, 405, KAIAMA ROAD, IIORIN KWARA STATE 8038099594 biorajpharmaceuticalltd@gmail.com BIORAJ PHARMACEUTICALS LTD., No. 405 Kaiama Road Ilorin,Kwara State, Nigeria | 21/12/2023 |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
ATC Group | Classification | |
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B03AE02 | Iron, multivitamins and folic acid | B Blood and blood forming organs → B03 Antianemic preparations → B03A Iron preparations → B03AE Iron in other combinations |
This drug has been assigned below unique identifiers within the countries it is being marketed:
Country | Identification scheme | Identifier(s) |
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NG | Registered Drug Product Database | A4-2431 |
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