VOLIGESIC PLUS

This brand name is authorized in Nigeria.

Active ingredients

The drug VOLIGESIC PLUS contains a combination of these active pharmaceutical ingredients (APIs):

`1`	Diclofenac UNII `6TGQ35Z71K` - DICLOFENAC DIETHYLAMINE
	Diclofenac is a non-steroidal anti-inflammatory drug. The mechanism of action of diclofenac in AK may be related to the inhibition of the cycloxygenase pathway leading to reduced prostaglandin E₂ (PGE₂) synthesis. In addition, immunohistochemistry (IHC) from skin biopsies ac revealed that the clinical effects of diclofenac in AK are primarily due to anti-inflammatory, anti-angiogenic and possibly anti-proliferative effects and apoptosis-inducing mechanisms.
	Read more about Diclofenac
`2`	Linseed oil UNII `84XB4DV00W` - LINSEED OIL
`3`	Menthol UNII `L7T10EIP3A` - MENTHOL, UNSPECIFIED FORM
	Read more about Menthol
`4`	Methyl salicylate UNII `LAV5U5022Y` - METHYL SALICYLATE
	Methyl salicylate has the action of salicylates, causing dilation of the skin vessels. Methyl salicylate is used to prevent bed sores and for hardening the skin of the feet.
	Read more about Methyl salicylate

Packages

This drug has been approved in Nigeria as follows:

Identifier	Form	Presentation	Description	Approval
A4-100135	Gel	Voligesic Plus Gel GEL 1%; 10%; 5%; 3%	1079 Diclofenac Diethylamine 1.1i%W/V, Linseed Oil 3%W/W, Methyl Salicylate 10%W/W, Menthol 5%W/W, Benzyl Alcohol 1%W/W, Gel Base Qs A4-100135 Voligesic Plus Gel Diclofenac Diethylamine, Linseed Oil, Methyl Salicylate, Menthol, Benzyl Alcohol Analgesics Cutaneous/Topical Route 1.1i%W/V, 3%W/W, 10%W/W, 5%W/W, 1%W/W Gel Over The Counter (Otc) First J Pocco Pharma Limited M/S Scott- Edil Pharmacia Ltd India 2021-10-28 2026-10-27	28/10/2021

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
NG	Registered Drug Product Database	A4-100135

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