ATC Group: V03AF03 Calcium folinate

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of V03AF03 in the ATC hierarchy

Level Code Title
1 V Various
2 V03 All other therapeutic products
3 V03A All other therapeutic products
4 V03AF Detoxifying agents for antineoplastic treatment
5 V03AF03 Calcium folinate

Defined daily dose

The DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults. The DDD is a unit of measurement and does not necessarily reflect the recommended or Prescribed Daily Dose. Therapeutic doses for individual patients and patient groups will often differ from the DDD as they will be based on individual characteristics (such as age, weight, ethnic differences, type and severity of disease) and pharmacokinetic considerations.

Route Amount
ORAL - Oral 60 mg
PAREN - Parenteral 60 mg

Active ingredients in V03AF03

Active Ingredient Description
Calcium folinate

Calcium folinate is an active metabolite of folinic acid and essential coenzyme for nucleic acid synthesis in cytotoxic therapy. Calcium folinate is frequently used to diminish the toxicity and counteract the action of folate antagonists, such as methotrexate.

Related product monographs

Title Information Source Document Type  
CALCIUM FOLINATE Solution for injection / infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
CALCIUM FOLINATE Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
REFOLINON Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Medicines in this ATC group

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Netherlands (NL)

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South Africa (ZA)

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United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.