Ephedrine

Chemical formula: C₁₀H₁₅NO  Molecular mass: 165.232 g/mol  PubChem compound: 9294

Active ingredient description

Ephedrine is a sympathomimetic amine acting directly on the alpha and beta receptors and indirectly by increasing the release of noradrenaline by the sympathetic nerve endings. As with any sympathomimetic agent, ephedrine stimulates the central nervous system, the cardiovascular system, the respiratory system, and the sphincters of the digestive and urinary systems.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C01CA26 Ephedrine C Cardiovascular system → C01 Cardiac therapy → C01C Cardiac stimulants excl. cardiac glycosides → C01CA Adrenergic and dopaminergic agents
Discover more medicines within C01CA26
R01AA03 Ephedrine R Respiratory system → R01 Nasal preparations → R01A Decongestants and other nasal preparations for topical use → R01AA Sympathomimetics, plain
Discover more medicines within R01AA03
R01AB05 Ephedrine R Respiratory system → R01 Nasal preparations → R01A Decongestants and other nasal preparations for topical use → R01AB Sympathomimetics, combinations excl. corticosteroids
Discover more medicines within R01AB05
R03CA02 Ephedrine R Respiratory system → R03 Drugs for obstructive airway diseases → R03C Adrenergics for systemic use → R03CA Alpha- and beta-adrenoreceptor agonists
Discover more medicines within R03CA02
S01FB02 Ephedrine S Sensory organs → S01 Ophthalmologicals → S01F Mydriatics and cycloplegics → S01FB Sympathomimetics excl. antiglaucoma preparations
Discover more medicines within S01FB02

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
EPHEDRINE HYDROCHLORIDE Solution for injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
EPHEDRINE 1.0% Nasal drops Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
EPHEDRINE HYDROCHLORIDE Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 50-98-6
DrugBank Drug: DB01364
KEGG Drug: D00124
PubChem Compound: 9294
RxNorm Ingredient: 3966
SNOMED-CT Concept: 387358007
Ephedrine (substance)
UNII Identifier: GN83C131XS
EPHEDRINE

Medicines

Ephedrine is an active ingredient of these brands:

United States (US)

Austria (AT)

Brazil (BR)

Cyprus (CY)

France (FR)

  • (combination) OTYLOL as EPHEDRINE HYDROCHLORIDE
  • (combination) RHINO SULFURYL as EPHEDRINE HYDROCHLORIDE

Hong Kong (HK)

  • EFMOL as EPHEDRINE HYDROCHLORIDE
  • SPINEFE as EPHEDRINE HYDROCHLORIDE

  • (combination) ACODIN as EPHEDRINE HYDROCHLORIDE
  • (combination) ACTCOFED as EPHEDRINE HYDROCHLORIDE
  • (combination) AENDY as EPHEDRINE HYDROCHLORIDE
  • (combination) ALSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) ANMEN as EPHEDRINE HYDROCHLORIDE
  • (combination) ANTICOL COUGH as EPHEDRINE HYDROCHLORIDE
  • (combination) ANTISSVES as Methylephedrine hydrochloride
  • (combination) ANTITUSS as EPHEDRINE HYDROCHLORIDE
  • (combination) ARACO as EPHEDRINE HYDROCHLORIDE
  • (combination) ARISTTO as EPHEDRINE HYDROCHLORIDE
  • (combination) ARSECOYL as EPHEDRINE HYDROCHLORIDE
  • (combination) ATINASAL as EPHEDRINE HYDROCHLORIDE
  • (combination) BAILIE as EPHEDRINE HYDROCHLORIDE
  • (combination) BESCOFED as EPHEDRINE HYDROCHLORIDE
  • (combination) BIO-SED as EPHEDRINE HYDROCHLORIDE
  • (combination) BISALTON as EPHEDRINE HYDROCHLORIDE
  • (combination) BOLSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) BROMESED as EPHEDRINE HYDROCHLORIDE
  • (combination) BROMETUSIN as EPHEDRINE HYDROCHLORIDE
  • (combination) BRONCOLIN as EPHEDRINE HYDROCHLORIDE
  • (combination) BRONKIN as EPHEDRINE HYDROCHLORIDE
  • (combination) BROSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) CAPOSIN as EPHEDRINE HYDROCHLORIDE
  • (combination) CARNETTI as EPHEDRINE HYDROCHLORIDE
  • (combination) CASIROL as EPHEDRINE HYDROCHLORIDE
  • (combination) CECOBOL as EPHEDRINE HYDROCHLORIDE
  • (combination) CECOL as EPHEDRINE HYDROCHLORIDE
  • (combination) CERTAINTY as EPHEDRINE HYDROCHLORIDE
  • (combination) CO-SEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) CO-TUSIN as EPHEDRINE HYDROCHLORIDE
  • (combination) CO-TUSIU as EPHEDRINE HYDROCHLORIDE
  • (combination) COBELIN as EPHEDRINE HYDROCHLORIDE
  • (combination) COBO as EPHEDRINE HYDROCHLORIDE
  • (combination) COCILLIN as EPHEDRINE HYDROCHLORIDE
  • (combination) COCLEAN as EPHEDRINE HYDROCHLORIDE
  • (combination) COCURE as EPHEDRINE HYDROCHLORIDE
  • (combination) CODAEWON as Methylephedrine
  • (combination) CODE-C as Methylephedrine
  • (combination) CODENAL as Methylephedrine
  • (combination) CODENS as Methylephedrine
  • (combination) CODEY as EPHEDRINE HYDROCHLORIDE
  • (combination) CODIXINE as EPHEDRINE HYDROCHLORIDE
  • (combination) COFEDPO as EPHEDRINE HYDROCHLORIDE
  • (combination) COFETIN as EPHEDRINE HYDROCHLORIDE
  • (combination) COFETOL as EPHEDRINE HYDROCHLORIDE
  • (combination) COFFTIER as EPHEDRINE HYDROCHLORIDE
  • (combination) COFLUKON as EPHEDRINE HYDROCHLORIDE
  • (combination) COL-LERGIC as EPHEDRINE HYDROCHLORIDE
  • (combination) COLASED as EPHEDRINE HYDROCHLORIDE
  • (combination) COLESS COUGH as EPHEDRINE HYDROCHLORIDE
  • (combination) COLSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) COMEPHEN as EPHEDRINE HYDROCHLORIDE
  • (combination) COMETIN as EPHEDRINE HYDROCHLORIDE
  • (combination) CONDOSA as EPHEDRINE HYDROCHLORIDE
  • (combination) COPHENDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) COPHENSIN as EPHEDRINE HYDROCHLORIDE
  • (combination) CORIMOR as EPHEDRINE HYDROCHLORIDE
  • (combination) CORIN as EPHEDRINE HYDROCHLORIDE
  • (combination) CORME as EPHEDRINE HYDROCHLORIDE
  • (combination) CORY as EPHEDRINE HYDROCHLORIDE
  • (combination) CORYLIN as EPHEDRINE HYDROCHLORIDE
  • (combination) COSEDIN as EPHEDRINE HYDROCHLORIDE
  • (combination) COSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) COSO as EPHEDRINE HYDROCHLORIDE
  • (combination) COSOTAL as EPHEDRINE HYDROCHLORIDE
  • (combination) COSRO as EPHEDRINE HYDROCHLORIDE
  • (combination) COTALIN as EPHEDRINE HYDROCHLORIDE
  • (combination) COTIN as EPHEDRINE HYDROCHLORIDE
  • (combination) CROSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) CUPATUSSIN as EPHEDRINE HYDROCHLORIDE
  • (combination) DAMINE as EPHEDRINE HYDROCHLORIDE
  • (combination) DECOFFA as EPHEDRINE HYDROCHLORIDE
  • (combination) DECOL as EPHEDRINE HYDROCHLORIDE
  • (combination) DEWEAR COUGH as EPHEDRINE HYDROCHLORIDE
  • (combination) DEXCOFED as EPHEDRINE HYDROCHLORIDE
  • (combination) DEXCOPHAN COUGH as EPHEDRINE HYDROCHLORIDE
  • (combination) DEXTRODYL as EPHEDRINE HYDROCHLORIDE
  • (combination) DHASEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) DIMECO as EPHEDRINE HYDROCHLORIDE
  • (combination) DIPHECO as EPHEDRINE HYDROCHLORIDE
  • (combination) DIPHETAN as EPHEDRINE HYDROCHLORIDE
  • (combination) DOLOMIN as EPHEDRINE HYDROCHLORIDE
  • (combination) ECOLIN as EPHEDRINE HYDROCHLORIDE
  • (combination) ECOMET as EPHEDRINE HYDROCHLORIDE
  • (combination) ECOPHEN as EPHEDRINE HYDROCHLORIDE
  • (combination) ECOSIN as EPHEDRINE HYDROCHLORIDE
  • (combination) EDENA as EPHEDRINE HYDROCHLORIDE
  • (combination) EENDEL LIGHT as EPHEDRINE HYDROCHLORIDE
  • (combination) EFENDEL as EPHEDRINE HYDROCHLORIDE
  • (combination) EFFECO COUGH as EPHEDRINE HYDROCHLORIDE
  • (combination) EIONE COUGH as EPHEDRINE HYDROCHLORIDE
  • (combination) EMORCO as EPHEDRINE HYDROCHLORIDE
  • (combination) ENAMIDE as EPHEDRINE HYDROCHLORIDE
  • (combination) EPHCOUGH as EPHEDRINE HYDROCHLORIDE
  • (combination) EPHECO as EPHEDRINE HYDROCHLORIDE
  • (combination) EPHEDYL DM as EPHEDRINE HYDROCHLORIDE
  • (combination) EPHEMO as EPHEDRINE HYDROCHLORIDE
  • (combination) EPHENDYLN as EPHEDRINE HYDROCHLORIDE
  • (combination) EPITON as EPHEDRINE HYDROCHLORIDE
  • (combination) ETACOL as EPHEDRINE HYDROCHLORIDE
  • (combination) EUROSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) FAMISEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) FARCOLIN as EPHEDRINE HYDROCHLORIDE
  • (combination) FENCO COUGH as EPHEDRINE HYDROCHLORIDE
  • (combination) FENCODYL as EPHEDRINE HYDROCHLORIDE
  • (combination) FENCOLIN COUGH as EPHEDRINE HYDROCHLORIDE
  • (combination) FENDIL as EPHEDRINE HYDROCHLORIDE
  • (combination) FENDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) FERRALI as EPHEDRINE HYDROCHLORIDE
  • (combination) FESCOFED as EPHEDRINE HYDROCHLORIDE
  • (combination) FOLSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) FRICOLIN as EPHEDRINE HYDROCHLORIDE
  • (combination) GECOL as EPHEDRINE HYDROCHLORIDE
  • (combination) GOBY COUGH as EPHEDRINE HYDROCHLORIDE
  • (combination) GROSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) GUSILON COUGH as EPHEDRINE HYDROCHLORIDE
  • (combination) HOLSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) IPENIN as EPHEDRINE HYDROCHLORIDE
  • (combination) IPESED as EPHEDRINE HYDROCHLORIDE
  • (combination) JENDEL as EPHEDRINE HYDROCHLORIDE
  • (combination) JENDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) JIKODIN as EPHEDRINE HYDROCHLORIDE
  • (combination) KARCINHO as EPHEDRINE HYDROCHLORIDE
  • (combination) KASON as METHYLEPHEDRINE HYDROCHLORIDE
  • (combination) KATALIN as EPHEDRINE HYDROCHLORIDE
  • (combination) KENDEL as EPHEDRINE HYDROCHLORIDE
  • (combination) KOLSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) KONTUSSIN as EPHEDRINE HYDROCHLORIDE
  • (combination) KROSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) LAMBAR as EPHEDRINE HYDROCHLORIDE
  • (combination) LAVENDA as EPHEDRINE HYDROCHLORIDE
  • (combination) LECOL as EPHEDRINE HYDROCHLORIDE
  • (combination) LIBERIN as EPHEDRINE HYDROCHLORIDE
  • (combination) LOLSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) MARSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) MARUSEN as EPHEDRINE HYDROCHLORIDE
  • (combination) MECODIN as EPHEDRINE HYDROCHLORIDE
  • (combination) MEGATUSSIC as EPHEDRINE HYDROCHLORIDE
  • (combination) MEPHENDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) MERSIDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) MESADIN as EPHEDRINE HYDROCHLORIDE
  • (combination) METASIN as EPHEDRINE HYDROCHLORIDE
  • (combination) METHARINE as EPHEDRINE HYDROCHLORIDE
  • (combination) METHOPIME as EPHEDRINE HYDROCHLORIDE
  • (combination) METHORSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) MONIC COUGH as EPHEDRINE HYDROCHLORIDE
  • (combination) MROSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) MYCODIN as EPHEDRINE HYDROCHLORIDE
  • (combination) NASALTON as EPHEDRINE HYDROCHLORIDE
  • (combination) NASEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) NAVOSE as EPHEDRINE HYDROCHLORIDE
  • (combination) NOLSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) NORVICOL as EPHEDRINE HYDROCHLORIDE
  • (combination) OROSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) PECOLIN as EPHEDRINE HYDROCHLORIDE
  • (combination) PEMASIL as EPHEDRINE HYDROCHLORIDE
  • (combination) PHECOBO as EPHEDRINE HYDROCHLORIDE
  • (combination) PHECOLIN as EPHEDRINE HYDROCHLORIDE
  • (combination) PHECOMIN-N as EPHEDRINE HYDROCHLORIDE
  • (combination) PHENAZOL as EPHEDRINE HYDROCHLORIDE
  • (combination) PHENCOUGH as EPHEDRINE HYDROCHLORIDE
  • (combination) PHENSEDYN as EPHEDRINE HYDROCHLORIDE
  • (combination) PHENTAGON as EPHEDRINE HYDROCHLORIDE
  • (combination) PHENZINCO as EPHEDRINE HYDROCHLORIDE
  • (combination) POCODYL as EPHEDRINE HYDROCHLORIDE
  • (combination) POLESEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) POSODIN as EPHEDRINE HYDROCHLORIDE
  • (combination) PRADASON as EPHEDRINE HYDROCHLORIDE
  • (combination) PRESEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) PRO-COTIN as EPHEDRINE HYDROCHLORIDE
  • (combination) PRO-PHECO as EPHEDRINE HYDROCHLORIDE
  • (combination) PROCODINE as EPHEDRINE HYDROCHLORIDE
  • (combination) PROCOSED as EPHEDRINE HYDROCHLORIDE
  • (combination) PROCOTUSS as EPHEDRINE HYDROCHLORIDE
  • (combination) PRODEX as EPHEDRINE HYDROCHLORIDE
  • (combination) PROPHENIN ELIXIR as EPHEDRINE HYDROCHLORIDE
  • (combination) PROSEDIN as EPHEDRINE HYDROCHLORIDE
  • (combination) PROSEDINE as EPHEDRINE HYDROCHLORIDE
  • (combination) PROSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) PROSODIN as EPHEDRINE HYDROCHLORIDE
  • (combination) QUENCOL as EPHEDRINE HYDROCHLORIDE
  • (combination) RROSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) SECOLIN-F as EPHEDRINE HYDROCHLORIDE
  • (combination) SEDCOLINE as EPHEDRINE HYDROCHLORIDE
  • (combination) SEDYLIN as EPHEDRINE HYDROCHLORIDE
  • (combination) SENDY as EPHEDRINE HYDROCHLORIDE
  • (combination) SOLSEDYL COUGH as EPHEDRINE HYDROCHLORIDE
  • (combination) SUPERPLEX as EPHEDRINE HYDROCHLORIDE
  • (combination) SUPHENIN as EPHEDRINE HYDROCHLORIDE
  • (combination) SURSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) SURTUSSIN as EPHEDRINE HYDROCHLORIDE
  • (combination) SUTACO COUGH as EPHEDRINE HYDROCHLORIDE
  • (combination) TANCOMIN as EPHEDRINE HYDROCHLORIDE
  • (combination) TARVONIL as EPHEDRINE HYDROCHLORIDE
  • (combination) TIXCO COUGH as EPHEDRINE HYDROCHLORIDE
  • (combination) TOLSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) TOUSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) TRICOS COUGH as EPHEDRINE HYDROCHLORIDE
  • (combination) TROSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) TUCOSOL as EPHEDRINE HYDROCHLORIDE
  • (combination) TUCOUSOL as EPHEDRINE HYDROCHLORIDE
  • (combination) TUSINCO as EPHEDRINE HYDROCHLORIDE
  • (combination) TUSSIC as EPHEDRINE HYDROCHLORIDE
  • (combination) TUSSORAL as EPHEDRINE HYDROCHLORIDE
  • (combination) U-PHENCO as EPHEDRINE HYDROCHLORIDE
  • (combination) UNI-COLIN as EPHEDRINE HYDROCHLORIDE
  • (combination) VANDAFU as EPHEDRINE HYDROCHLORIDE
  • (combination) VOLSEDYL COUGH as EPHEDRINE HYDROCHLORIDE
  • (combination) WASEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) WINSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) XOLSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) ZECOL COUGH as EPHEDRINE HYDROCHLORIDE
  • (combination) ZOLLAR as EPHEDRINE HYDROCHLORIDE

Israel (IL)

Japan (JP)

  • METHY-F as Methylephedrine

  • (combination) CHLOPHEDRIN S as Methylephedrine
  • (combination) COUGHCODE-N as Methylephedrine
  • (combination) HUSCODE as METHYLEPHEDRINE HYDROCHLORIDE, (+/-)-
  • (combination) MUCOBROTIN as Dl-Methylephedrine hydrochloride
  • (combination) SEKICODE as EPHEDRINE HYDROCHLORIDE

Nigeria (NG)

Poland (PL)

  • EFRINOL as EPHEDRINE HYDROCHLORIDE

Romania (RO)

  • (combination) BIXTONIM as EPHEDRINE HYDROCHLORIDE
  • (combination) RINONEF T as EPHEDRINE HYDROCHLORIDE

Singapore (SG)

  • (combination) ALCOUGH as EPHEDRINE HYDROCHLORIDE
  • (combination) BRECOLIN as EPHEDRINE HYDROCHLORIDE
  • (combination) CHLORSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) COPHADYL-E as EPHEDRINE HYDROCHLORIDE
  • (combination) COUGHLAX as EPHEDRINE HYDROCHLORIDE
  • (combination) DECOFAM as EPHEDRINE HYDROCHLORIDE
  • (combination) DEXCOPHAN COUGH as EPHEDRINE HYDROCHLORIDE
  • (combination) DHASEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) DIPRODIN as EPHEDRINE HYDROCHLORIDE
  • (combination) POLINS COUGH MIXTURE as EPHEDRINE HYDROCHLORIDE
  • (combination) PROMEDYL-B as EPHEDRINE HYDROCHLORIDE
  • (combination) SEMERIN as EPHEDRINE HYDROCHLORIDE
  • (combination) SUNSEDYL as EPHEDRINE HYDROCHLORIDE
  • (combination) UNISEDYL FORTE as EPHEDRINE HYDROCHLORIDE

South Africa (ZA)

Spain (ES)

  • (combination) CODINEX as EPHEDRINE HYDROCHLORIDE
  • (combination) HEMOAL as EPHEDRINE HYDROCHLORIDE

Tunisia (TN)

  • (combination) OSMOTOL as EPHEDRINE HYDROCHLORIDE

Turkey (TR)

  • RINITALMIT

  • (combination) ANTIBEKSIN as EPHEDRINE HYDROCHLORIDE
  • (combination) BROKSIN as EPHEDRINE HYDROCHLORIDE
  • (combination) BRONKOFLU as EPHEDRINE HYDROCHLORIDE
  • (combination) DEFEKS as EPHEDRINE HYDROCHLORIDE
  • (combination) DORFAN as EPHEDRINE HYDROCHLORIDE
  • (combination) EUPNASE as EPHEDRINE HYDROCHLORIDE
  • (combination) LUDICODINE as EPHEDRINE HYDROCHLORIDE
  • (combination) OKODIN as EPHEDRINE HYDROCHLORIDE
  • (combination) OPSIS as EPHEDRINE HYDROCHLORIDE
  • (combination) SULFARHIN as EPHEDRINE HYDROCHLORIDE
  • (combination) TUSIPAN as EPHEDRINE HYDROCHLORIDE

United Kingdom (UK)

  • EPHEDRINE as EPHEDRINE HYDROCHLORIDE

  • (combination) HAYMINE as EPHEDRINE HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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