Frovatriptan

Chemical formula: C₁₄H₁₇N₃O  Molecular mass: 243.304 g/mol  PubChem compound: 77992

Active ingredient description

Frovatriptan is a selective agonist for 5-HT receptors. Frovatriptan is believed to act selectively on extracerebral, intracranial arteries to inhibit the excessive dilatation of these vessels in migraine.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N02CC07 Frovatriptan N Nervous system → N02 Analgesics → N02C Antimigraine preparations → N02CC Selective serotonin (5HT1) agonists
Discover more medicines within N02CC07

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
MIGARD Film-coated tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
FROVA Tablet FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 158747-02-5
DrugBank Drug: DB00998
KEGG Drug: D07997
PubChem Compound: 77992
RxNorm Ingredient: 228783
SNOMED-CT Concept: 411990007
Frovatriptan (substance)
UNII Identifier: H82Q2D5WA7
FROVATRIPTAN

Medicines

Frovatriptan is an active ingredient of these brands:

United States (US)

  • FROVA as FROVATRIPTAN SUCCINATE

Austria (AT)

Canada (CA)

  • FROVA as FROVATRIPTAN SUCCINATE

Croatia (HR)

Estonia (EE)

  • MIGARD as FROVATRIPTAN SUCCINATE

Finland (FI)

France (FR)

  • ISIMIG as FROVATRIPTAN SUCCINATE
  • TIGREAT as FROVATRIPTAN SUCCINATE

Germany (DE)

  • EUMITAN as FROVATRIPTAN SUCCINATE

Ireland (IE)

Italy (IT)

Lithuania (LT)

  • MIGARD as FROVATRIPTAN SUCCINATE

Netherlands (NL)

Spain (ES)

  • FORVEY as FROVATRIPTAN SUCCINATE

Tunisia (TN)

  • RILAMIG as FROVATRIPTAN SUCCINATE

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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