Lamivudine Other names: 3TC

Chemical formula: C₈H₁₁N₃O₃S  Molecular mass: 229.256 g/mol  PubChem compound: 60825

Active ingredient description

Lamivudine is a nucleoside analogue which has activity against human immunodeficiency virus (HIV) and hepatitis B virus (HBV). Its main mode of action is as a chain terminator of viral reverse transcription.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J05AF05 Lamivudine J Antiinfectives for systemic use → J05 Antivirals for systemic use → J05A Direct acting antivirals → J05AF Nucleoside and nucleotide reverse transcriptase inhibitors
Discover more medicines within J05AF05

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
EPIVIR Film-coated tablet European Medicines Agency (EU) MPI, EU: SmPC
EPIVIR Oral solution European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 131086-21-0
CAS Substance: 134678-17-4
DrugBank Drug: DB00709
KEGG Drug: D00353
PubChem Compound: 60825
RxNorm Ingredient: 68244
SNOMED-CT Concept: 386897000
Lamivudine (substance)
UNII Identifier: 2T8Q726O95
LAMIVUDINE

Medicines

Lamivudine is an active ingredient of these brands:

United States (US)

Albania (AL)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

Hong Kong (HK)

Ireland (IE)

Israel (IL)

Italy (IT)

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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