Moxifloxacin

Chemical formula: C₂₁H₂₄FN₃O₄  Molecular mass: 401.431 g/mol  PubChem compound: 152946

Active ingredient description

Moxifloxacin, a fourth-generation fluoroquinolone, has in vitro activity against a wide range of Gram-positive and Gram-negative pathogens. The bactericidal action of moxifloxacin results from the inhibition of both type II topoisomerases (DNA gyrase and topoisomerase IV) required for bacterial DNA replication, transcription and repair.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J01MA14 Moxifloxacin J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01M Quinolone antibacterials → J01MA Fluoroquinolones
Discover more medicines within J01MA14
S01AE07 S Sensory organs → S01 Ophthalmologicals → S01A Antiinfectives → S01AE Fluoroquinolones
Discover more medicines within S01AE07

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
AVELOX Solution for infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
MOXIVIG Eye drops Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
AVELOX Film-coated tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 151096-09-2
DrugBank Drug: DB00218
KEGG Drug: D08237
PubChem Compound: 152946
RxNorm Ingredient: 139462
SNOMED-CT Concept: 412439003
Moxifloxacin (substance)
UNII Identifier: U188XYD42P
MOXIFLOXACIN

Medicines

Moxifloxacin is an active ingredient of these brands:

United States (US)

  • MOXEZA as MOXIFLOXACIN HYDROCHLORIDE
  • VIGAMOX as MOXIFLOXACIN HYDROCHLORIDE

Austria (AT)

  • AVELOX as MOXIFLOXACIN HYDROCHLORIDE

Brazil (BR)

  • AVALOX as MOXIFLOXACIN HYDROCHLORIDE
  • MOCLAZOM as MOXIFLOXACIN HYDROCHLORIDE
  • MOXIBACTEN as MOXIFLOXACIN HYDROCHLORIDE
  • MOXICRIS as MOXIFLOXACIN HYDROCHLORIDE
  • NEUMOSIN as MOXIFLOXACIN HYDROCHLORIDE
  • PRAIVA as MOXIFLOXACIN HYDROCHLORIDE
  • VIGAMOX as MOXIFLOXACIN HYDROCHLORIDE

  • (combination) FACOBA as MOXIFLOXACIN HYDROCHLORIDE
  • (combination) VIGADEXA as MOXIFLOXACIN HYDROCHLORIDE

Canada (CA)

  • VIGAMOX as MOXIFLOXACIN HYDROCHLORIDE

Croatia (HR)

  • MOKSACIN as MOXIFLOXACIN HYDROCHLORIDE
  • MOLOXIN as MOXIFLOXACIN HYDROCHLORIDE

Cyprus (CY)

  • AVELOX as MOXIFLOXACIN HYDROCHLORIDE
  • ERELAN as MOXIFLOXACIN HYDROCHLORIDE
  • VIGAMOX as MOXIFLOXACIN HYDROCHLORIDE

Ecuador (EC)

Estonia (EE)

Finland (FI)

  • AVELOX as MOXIFLOXACIN HYDROCHLORIDE
  • VIGAMOX as MOXIFLOXACIN HYDROCHLORIDE

France (FR)

  • IZILOX as MOXIFLOXACIN HYDROCHLORIDE

Germany (DE)

  • AVALOX as MOXIFLOXACIN HYDROCHLORIDE

Hong Kong (HK)

  • AVELOX as MOXIFLOXACIN HYDROCHLORIDE
  • MOXICIN as MOXIFLOXACIN HYDROCHLORIDE
  • MOXIGET as MOXIFLOXACIN HYDROCHLORIDE
  • PRAXINSTAD as MOXIFLOXACIN HYDROCHLORIDE
  • RIVOMOXI as MOXIFLOXACIN HYDROCHLORIDE
  • VIGAMOX as MOXIFLOXACIN HYDROCHLORIDE

Ireland (IE)

  • AVELOX as MOXIFLOXACIN HYDROCHLORIDE

Israel (IL)

  • MEGAXIN as MOXIFLOXACIN HYDROCHLORIDE
  • VIGAMOX as MOXIFLOXACIN HYDROCHLORIDE

Italy (IT)

  • AVALOX as MOXIFLOXACIN HYDROCHLORIDE

Japan (JP)

  • AVELOX as MOXIFLOXACIN HYDROCHLORIDE
  • VEGAMOX as MOXIFLOXACIN HYDROCHLORIDE

Lithuania (LT)

Malta (MT)

  • AVELOX as MOXIFLOXACIN HYDROCHLORIDE
  • ERELAN as MOXIFLOXACIN HYDROCHLORIDE
  • VIGAMOX as MOXIFLOXACIN HYDROCHLORIDE

Mexico (MX)

  • AVELOX as MOXIFLOXACIN HYDROCHLORIDE
  • VIGAMOXI as MOXIFLOXACIN HYDROCHLORIDE

  • (combination) VIGADEXA as MOXIFLOXACIN HYDROCHLORIDE

Netherlands (NL)

  • VIGAMOX as MOXIFLOXACIN HYDROCHLORIDE

New Zealand (NZ)

  • AVELOX as MOXIFLOXACIN HYDROCHLORIDE

Nigeria (NG)

Poland (PL)

  • FLOMIXA as MOXIFLOXACIN HYDROCHLORIDE
  • FLOXAMIC as MOXIFLOXACIN HYDROCHLORIDE
  • FLOXITRAT as MOXIFLOXACIN HYDROCHLORIDE
  • KIMOKS as MOXIFLOXACIN HYDROCHLORIDE
  • MOLOXIN as MOXIFLOXACIN HYDROCHLORIDE
  • MONAFOX as MOXIFLOXACIN HYDROCHLORIDE
  • MOXINEA as MOXIFLOXACIN HYDROCHLORIDE
  • PELLISOREC as MOXIFLOXACIN HYDROCHLORIDE
  • VIGAMOX as MOXIFLOXACIN HYDROCHLORIDE
  • XIFLODROP as MOXIFLOXACIN HYDROCHLORIDE

Romania (RO)

  • AVELOX as MOXIFLOXACIN HYDROCHLORIDE
  • ERELAN as MOXIFLOXACIN HYDROCHLORIDE
  • KIMOKS as MOXIFLOXACIN HYDROCHLORIDE
  • MOFLAXA as MOXIFLOXACIN HYDROCHLORIDE
  • VIGAMOX as MOXIFLOXACIN HYDROCHLORIDE

Singapore (SG)

  • AVELOX as MOXIFLOXACIN HYDROCHLORIDE
  • FLOXSAFE as MOXIFLOXACIN HYDROCHLORIDE
  • JOYLOXIN as MOXIFLOXACIN HYDROCHLORIDE
  • MO-FLOREN as MOXIFLOXACIN HYDROCHLORIDE
  • MOLOXIN as MOXIFLOXACIN HYDROCHLORIDE
  • MOXETERO as MOXIFLOXACIN HYDROCHLORIDE
  • VIGAMOX as MOXIFLOXACIN HYDROCHLORIDE

South Africa (ZA)

Spain (ES)

  • ABIMOX
  • ABIOX as MOXIFLOXACIN HYDROCHLORIDE
  • ACTIRA as MOXIFLOXACIN HYDROCHLORIDE
  • ERELAN as MOXIFLOXACIN HYDROCHLORIDE
  • VIGAMOX as MOXIFLOXACIN HYDROCHLORIDE

Turkey (TR)

  • ATAFLOKS
  • AVELOX as MOXIFLOXACIN HYDROCHLORIDE
  • BIVOXA as MOXIFLOXACIN HYDROCHLORIDE
  • DEMOXIF as MOXIFLOXACIN HYDROCHLORIDE
  • EMESMOX as MOXIFLOXACIN HYDROCHLORIDE
  • MOFELOX as MOXIFLOXACIN HYDROCHLORIDE
  • MOKSEFEN as MOXIFLOXACIN HYDROCHLORIDE
  • MOKSILOX as MOXIFLOXACIN HYDROCHLORIDE
  • MOXACIN as MOXIFLOXACIN HYDROCHLORIDE
  • MOXAFLOX as MOXIFLOXACIN HYDROCHLORIDE
  • MOXAI as MOXIFLOXACIN HYDROCHLORIDE
  • MOXDAY as MOXIFLOXACIN HYDROCHLORIDE
  • MOXHEL as MOXIFLOXACIN HYDROCHLORIDE
  • MOXICUM as MOXIFLOXACIN HYDROCHLORIDE
  • MOXIFIX
  • MOXIFOR as MOXIFLOXACIN HYDROCHLORIDE
  • MOXIITEC as MOXIFLOXACIN HYDROCHLORIDE
  • MOXIPREC as MOXIFLOXACIN HYDROCHLORIDE
  • MOXITAB as MOXIFLOXACIN HYDROCHLORIDE
  • MOXITEC as MOXIFLOXACIN HYDROCHLORIDE
  • PITOXIL as MOXIFLOXACIN HYDROCHLORIDE
  • PNEMOX as MOXIFLOXACIN HYDROCHLORIDE
  • VIGAMOX as MOXIFLOXACIN HYDROCHLORIDE

  • (combination) BIVOXA-D as MOXIFLOXACIN HYDROCHLORIDE
  • (combination) MOXIDEXA as MOXIFLOXACIN HYDROCHLORIDE

United Kingdom (UK)

  • AVELOX as MOXIFLOXACIN HYDROCHLORIDE
  • MOXIVIG as MOXIFLOXACIN HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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