Propranolol

Chemical formula: C₁₆H₂₁NO₂  Molecular mass: 259.343 g/mol  PubChem compound: 4946

Active ingredient description

Propranolol is a competitive antagonist at both beta, and beta2-adrenoceptor, but has membrane stabilising activity at concentrations exceeding 1-3mg/litre, though such concentrations are rarely achieved during oral therapy. Competitive beta-blockade has been demonstrated in man by a parallel shift to the right in the dose-heart rate response curve to beta-agonists such as isoprenaline.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C07AA05 Propranolol C Cardiovascular system → C07 Beta blocking agents → C07A Beta blocking agents → C07AA Beta blocking agents, non-selective
Discover more medicines within C07AA05

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
PROPANOLOL Film-coated tablets Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
HEMANGIOL Oral solution European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 318-98-9
CAS Substance: 525-66-6
DrugBank Drug: DB00571
KEGG Drug: D08443
PubChem Compound: 4946
RxNorm Ingredient: 8787
SNOMED-CT Concept: 372772003
Propranolol (substance)
UNII Identifier: 9Y8NXQ24VQ
PROPRANOLOL

Medicines

Propranolol is an active ingredient of these brands:

United States (US)

Australia (AU)

  • DERALIN as PROPRANOLOL HYDROCHLORIDE
  • INDERAL as PROPRANOLOL HYDROCHLORIDE

Austria (AT)

Brazil (BR)

Canada (CA)

Croatia (HR)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Germany (DE)

  • DOCITON as PROPRANOLOL HYDROCHLORIDE
  • INDERAL as PROPRANOLOL HYDROCHLORIDE
  • OBSIDAN as PROPRANOLOL HYDROCHLORIDE

  • (combination) DOCITEREN as PROPRANOLOL HYDROCHLORIDE

Hong Kong (HK)

  • BECARDIN as PROPRANOLOL HYDROCHLORIDE
  • BETAPRESS as PROPRANOLOL HYDROCHLORIDE
  • DERALIN as PROPRANOLOL HYDROCHLORIDE
  • PRALOL as PROPRANOLOL HYDROCHLORIDE
  • PROLOL as PROPRANOLOL HYDROCHLORIDE
  • PROPA as PROPRANOLOL HYDROCHLORIDE
  • SYNOLOL as PROPRANOLOL HYDROCHLORIDE

Ireland (IE)

Israel (IL)

  • HEMANGIOL as PROPRANOLOL HYDROCHLORIDE
  • PROLOL as PROPRANOLOL HYDROCHLORIDE

Japan (JP)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Romania (RO)

Singapore (SG)

South Africa (ZA)

Spain (ES)

  • HEMANGIOL as PROPRANOLOL HYDROCHLORIDE
  • SUMIAL as PROPRANOLOL HYDROCHLORIDE

Tunisia (TN)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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