Urapidil

Chemical formula: C₂₀H₂₉N₅O₃  Molecular mass: 387.484 g/mol  PubChem compound: 5639

Active ingredient description

Urapidil is a α1-adrenoceptor antagonist and 5-HT1A receptor agonist and consequently inhibits the vasoconstrictor effect of catecholamines. It interacts with peripheral α1-adrenoceptors and central 5-HT1A receptors to produce vasodilation without sympathetic activation.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
C02CA06 Urapidil C Cardiovascular system → C02 Antihypertensives → C02C Antiadrenergic agents, peripherally acting → C02CA Alpha-adrenoreceptor antagonists
Discover more medicines within C02CA06

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
URAPIDIL Prolonged-release capsule, hard MPI, EU: SmPC
URAPIDIL Solution for injection MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 34661-75-1
DrugBank Drug: DB12661
PubChem Compound: 5639
RxNorm Ingredient: 39230
SNOMED-CT Concept: 698807007
Urapidil (substance)
UNII Identifier: A78GF17HJS
URAPIDIL

Medicines

Urapidil is an active ingredient of these brands:

Croatia (HR)

Ecuador (EC)

Estonia (EE)

France (FR)

Germany (DE)

Japan (JP)

Lithuania (LT)

Poland (PL)

Romania (RO)

Spain (ES)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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