Valbenazine

Chemical formula: C₂₄H₃₈N₂O₄  Molecular mass: 418.578 g/mol  PubChem compound: 24795069

Active ingredient description

The mechanism of action of valbenazine for the treatment of tardive dyskinesia and chorea in patients with Huntington’s disease is unclear, but is thought to be mediated through the reversible inhibition of vesicular monoamine transporter 2 (VMAT2), a transporter that regulates monoamine uptake from the cytoplasm to the synaptic vesicle for storage and release.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N07XX13 N Nervous system → N07 Other nervous system drugs → N07X Other nervous system drugs → N07XX Other nervous system drugs
Discover more medicines within N07XX13

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
INGREZZA Capsule FDA, National Drug Code (US) MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 1025504-45-3
DrugBank Drug: DB11915
PubChem Compound: 24795069
RxNorm Ingredient: 1918219
SNOMED-CT Concept: 733727001
Valbenazine (substance)
UNII Identifier: 54K37P50KH
VALBENAZINE

Medicines

Valbenazine is an active ingredient of these brands:

United States (US)

Japan (JP)

  • DYSVAL as VALBENAZINE TOSYLATE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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