ATC Group: A03AX Other drugs for functional bowel disorders

Alverine is a drug used for functional gastrointestinal disorders. Alverine is a smooth muscle relaxant used to relieve cramps or spasms of the stomach and intestines. It acts directly on the muscle in the gut, causing it to relax. It is used in the treatment of irritable bowel syndrome. It has a role as an antispasmodic drug.

Dimeticone is used in many pharmaceutical and cosmetic preparations. A 4% concentration has been found to affect the physico-physiological activity of lice.

Fenoverine is a calcium antagonist that inhibits the calcium channels at significant sites in the calcium transport system. It stops the rapid calcium influx through the voltage-dependent channels and inhibits the rapid calcium release from the intracellular storage sites. This induces an effect on the strong (transient and prolonged), asynchronous spasmodic contractions. Fenoverine is a potent, musculotropic, spasmolytic agent that affects primarily the gastrointestinal tract, bile duct, and female genital organs.

Simethicone is a chemically inert, non-systemic gastric defoaming agent that works by altering the elasticity of interfaces of mucus-embedded bubbles in the gastrointestinal tract. The gas bubbles are thus broken down or coalesced and in this form gas is more easily eliminated through eructation or passing flatus.