ATC Group: A05AX Other drugs for bile therapy

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of A05AX in the ATC hierarchy

Level Code Title
1 A Alimentary tract and metabolism
2 A05 Bile and liver therapy
3 A05A Bile therapy
4 A05AX Other drugs for bile therapy

Group A05AX contents

Code Title
A05AX01 Piprozolin
A05AX02 Hymecromone
A05AX03 Cyclobutyrol
A05AX04
A05AX05
A05AX06

Active ingredients in A05AX

Active Ingredient Description
Maralixibat

Maralixibat is a minimally absorbed, reversible, potent, selective inhibitor of the ileal bile acid transporter (IBAT). Maralixibat acts locally in the distal ileum to decrease the reuptake of bile acids and increase the clearance of bile acids through the colon, reducing the concentration of bile acids in the serum.

Odevixibat

Odevixibat is a reversible, potent, selective inhibitor of the ileal bile acid transporter (IBAT). Odevixibat acts locally in the distal ileum to decrease the reuptake of bile acids and increase the clearance of bile acids through the colon, reducing the concentration of bile acids in the serum. The extent of reduction of serum bile acids does not correlate with systemic PK.

Related product monographs

Title Information Source Document Type  
BYLVAY Hard capsule European Medicines Agency (EU) MPI, EU: SmPC
IQIRVO Film-coated tablet FDA, National Drug Code (US) MPI, US: SPL/PLR
LIVMARLI Oral solution European Medicines Agency (EU) MPI, EU: SmPC