ATC Group: A16AB24 Pegzilarginase

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of A16AB24 in the ATC hierarchy

Level Code Title
1 A Alimentary tract and metabolism
2 A16 Other alimentary tract and metabolism products
3 A16A Other alimentary tract and metabolism products
4 A16AB Enzymes
5 A16AB24

Active ingredients in A16AB24

Active Ingredient

Pegzilarginase is a cobalt substituted recombinant human arginase 1 enzyme conjugated with mPEG carriers. The mPEG carrier reduces clearance of pegzilarginase resulting in an extended half-life while maintaining the functions of the enzyme. Pegzilarginase is intended to substitute for the deficient human arginase 1 enzyme activity in patients with ARG1-D. Pegzilarginase has been shown to rapidly and sustainably reduce plasma arginine and convert it to urea and ornithine.

Related product monographs

Document Type Information Source  
 LOARGYS Solution for injection/infusion MPI, EU: SmPC European Medicines Agency (EU)

Medicines classified under this ATC code globally

Austria (AT)

Croatia (HR)

Estonia (EE)

France (FR)

Italy (IT)

Lithuania (LT)

Spain (ES)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.