ATC Group: A16AX03 Sodium phenylbutyrate

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of A16AX03 in the ATC hierarchy

Level Code Title
1 A Alimentary tract and metabolism
2 A16 Other alimentary tract and metabolism products
3 A16A Other alimentary tract and metabolism products
4 A16AX Various alimentary tract and metabolism products
5 A16AX03 Sodium phenylbutyrate

Defined daily dose

The DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults. The DDD is a unit of measurement and does not necessarily reflect the recommended or Prescribed Daily Dose. Therapeutic doses for individual patients and patient groups will often differ from the DDD as they will be based on individual characteristics (such as age, weight, ethnic differences, type and severity of disease) and pharmacokinetic considerations.

Route Amount
ORAL - Oral 20 g

Active ingredients in A16AX03

Active Ingredient Description
Sodium phenylbutyrate

Sodium phenylbutyrate is a pro-drug and is rapidly metabolised to phenylacetate. Phenylacetate is a metabolically active compound that conjugates with glutamine via acetylation to form phenylacetylglutamine which is then excreted by the kidneys. On a molar basis, phenylacetylglutamine is comparable to urea (each containing 2 moles of nitrogen) and therefore provides an alternate vehicle for waste nitrogen excretion.

Related product monographs

Title Information Source Document Type  
AMMONAPS Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
PHEBURANE Granules European Medicines Agency (EU) MPI, EU: SmPC

Medicines in this ATC group

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Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.