ATC Group: B05CA Antiinfectives

Cetylpyridinium is an antiseptic with activity against both gram positive and gram negative organisms.

Chlorhexidine is an antimicrobial agent, active against a broad spectrum of Gram-positive and Gram-negative organisms, yeasts, fungi, opportunistic anaerobes and aerobes. Chlorhexidine is mainly a “membrane-acting” agent that destroys the outer membrane of the bacteria. It is inactive on bacterial spores unless the temperatures are high.

Neomycin is an aminoglycoside antibiotic and acts by binding to polysomes, inhibiting protein synthesis and generating errors in the transcription of the genetic code.

Taurolidine inhibits the formation of postoperative peritoneal adhesions, and in vitro has been shown to reduce the adherence of micro-organisms to mucosal epithelium. The chemical mode of action of taurolidine via its reactive methylol groups confers greater potency in vivo than indicated by in vitro MIC values, and also appears to preclude susceptibility to resistance mechanisms.