The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
1
|
C | Cardiovascular system | |
2
|
C02 | Antihypertensives | |
3
|
C02K | Other antihypertensives | |
4
|
C02KB | Tyrosine hydroxylase inhibitors |
| Code | Title | |
|---|---|---|
| C02KB01 | Metirosine |
| Active Ingredient |
|---|
|
Metirosine inhibits tyrosine hydroxylase, which catalyzes the first transformation in catecholamine biosynthesis, i.e., the conversion of tyrosine to dihydroxyphenylalanine (DOPA). Because the first step is also the rate-limiting step, blockade of tyrosine hydroxylase activity results in decreased endogenous levels of catecholamines, usually measured as decreased urinary excretion of catecholamines and their metabolites. |
| Document | Type | Information Source | |
|---|---|---|---|
| DEMSER Capsule | MPI, US: SPL/Old | FDA, National Drug Code (US) |