The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
| 1 | C | Cardiovascular system | |
| 2 | C09 | Agents acting on the renin-angiotensin system | |
| 3 | C09X | Other agents acting on the renin-angiotensin system | |
| 4 | C09XA | Renin-inhibitors |
| Code | Title | |
|---|---|---|
| C09XA01 | Remikiren | |
| C09XA02 | Aliskiren | |
| C09XA52 | Aliskiren and hydrochlorothiazide | |
| C09XA53 | ||
| C09XA54 |
| Active Ingredient | Description | |
|---|---|---|
| Aliskiren |
Aliskiren is an orally active, non-peptide, potent and selective direct inhibitor of human renin. By inhibiting the enzyme renin, aliskiren inhibits the RAAS at the point of activation, blocking the conversion of angiotensinogen to angiotensin I and decreasing levels of angiotensin I and angiotensin II. |
|
| Aliskiren and Hydrochlorothiazide |
Combination of two antihypertensive active substances to control blood pressure in patients with essential hypertension. Aliskiren belongs to the class of direct renin inhibitors and hydrochlorothiazide to the class of thiazide diuretics. The combination of these substances with complementary mechanisms of action provides an additive antihypertensive effect, reducing blood pressure to a greater degree than either component alone. |
| Title | Information Source | Document Type | |
|---|---|---|---|
| RASILEZ Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC | |
| RASILEZ HCT Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC | |
| TEKTURNA Film-coated tablet | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
