The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
Level | Code | Title | |
---|---|---|---|
1 | J | Antiinfectives for systemic use | |
2 | J05 | Antivirals for systemic use | |
3 | J05A | Direct acting antivirals | |
4 | J05AJ | Integrase inhibitors |
Code | Title | |
---|---|---|
J05AJ01 | Raltegravir | |
J05AJ02 | ||
J05AJ03 | ||
J05AJ04 | Cabotegravir |
Active Ingredient | Description | |
---|---|---|
Cabotegravir |
Cabotegravir inhibits HIV integrase by binding to the integrase active site and blocking the strand transfer step of retroviral deoxyribonucleic acid (DNA) integration which is essential for the HIV replication cycle. |
|
Dolutegravir |
Dolutegravir inhibits HIV integrase by binding to the integrase active site and blocking the strand transfer step of retroviral Deoxyribonucleic acid (DNA) integration which is essential for the HIV replication cycle. |
|
Elvitegravir |
Elvitegravir, is a type of antiviral agent called an โintegrase inhibitorโ. It blocks an enzyme called integrase, which is involved in a step in the reproduction of HIV. When the enzyme is blocked, the virus cannot reproduce normally, slowing down the spread of infection. |
|
Raltegravir |
Raltegravir is an integrase strand transfer inhibitor active against the Human Immunodeficiency Virus (HIV-1). Raltegravir inhibits the catalytic activity of integrase, an HIV-encoded enzyme that is required for viral replication. Inhibition of integrase prevents the covalent insertion, or integration, of the HIV genome into the host cell genome. |
Title | Information Source | Document Type | |
---|---|---|---|
APRETUDE Prolonged-release suspension for injection | European Medicines Agency (EU) | MPI, EU: SmPC | |
ISENTRESS Chewable tablet | European Medicines Agency (EU) | MPI, EU: SmPC | |
ISENTRESS Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC | |
ISENTRESS Granules for oral suspension | European Medicines Agency (EU) | MPI, EU: SmPC | |
TIVICAY Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC | |
VOCABRIA Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC | |
VOCABRIA Film-coated tablet | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
VOCABRIA Prolonged-release suspension for injection | European Medicines Agency (EU) | MPI, EU: SmPC |