ATC Group: L01AC Ethylene imines

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of L01AC in the ATC hierarchy

Level Code Title
1 L Antineoplastic and immunomodulating agents
2 L01 Antineoplastic agents
3 L01A Alkylating agents
4 L01AC Ethylene imines

Group L01AC contents

Code Title
L01AC01 Thiotepa
L01AC02 Triaziquone
L01AC03 Carboquone

Active ingredients in L01AC

Active Ingredient Description
Carboquone

Carboquone is an anticancer alkylating agent, having chemical structure, 2,5-bis-(1-aziridinyl)3(2-carbamoyloxy-1-methoxyethyl)-6-methyl- 1,4- benzoquinone. The antitumor efficacies of carboquone were reported as excellent, however, the side effects are considerably strong.

Thiotepa

Thiotepa is a polyfunctional cytotoxic agent related chemically and pharmacologically to the nitrogen mustard. The radiomimetic action of thiotepa is believed to occur through the release of ethylene imine radicals that, as in the case of irradiation therapy, disrupt the bonds of DNA, e.g. by alkylation of guanine at the N-7, breaking the linkage between the purine base and the sugar and liberating alkylated guanine.

Related product monographs

Title Information Source Document Type  
TEPADINA Powder for concentrate for solution for infusion European Medicines Agency (EU) MPI, EU: SmPC