The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
| 1 | L | Antineoplastic and immunomodulating agents | |
| 2 | L01 | Antineoplastic agents | |
| 3 | L01D | Cytotoxic antibiotics and related substances | |
| 4 | L01DB | Anthracyclines and related substances | |
| 5 | L01DB04 | Aclarubicin |
| Active Ingredient | Description | |
|---|---|---|
| Aclarubicin |
Aclarubicin is an anthracycline antibiotic produced by Streptomyces galilaeus and also has potent antineoplastic activity. It is less cardiotoxic than doxorubicin and daunorubicin. The mechanism of action of aclarubicin is based on its capacity to insert its trisaccharide chain into the minor DNA groove: poison of topoisomerase I, inhibitor of topoisomerase II, eviction of histones from nucleosomes, but also inhibitor of the 20S proteasome. |
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.
