ATC Group: L02AE02 Leuprorelin

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of L02AE02 in the ATC hierarchy

Level Code Title
1 L Antineoplastic and immunomodulating agents
2 L02 Endocrine therapy
3 L02A Hormones and related agents
4 L02AE Gonadotropin releasing hormone analogues
5 L02AE02 Leuprorelin

Defined daily dose

The DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults. The DDD is a unit of measurement and does not necessarily reflect the recommended or Prescribed Daily Dose. Therapeutic doses for individual patients and patient groups will often differ from the DDD as they will be based on individual characteristics (such as age, weight, ethnic differences, type and severity of disease) and pharmacokinetic considerations.

Route Amount
PAREN - Parenteral 1 mg
PAREN - Parenteral (depot) 134 mg
SC - Subcutaneous (implant) 60 ug

Active ingredients in L02AE02

Active Ingredient Description
Leuprorelin

Leuprorelin is inactive when given orally due to poor membrane permeability and an almost complete inactivation by intestinal proteolytic enzymes. Leuprorelin has potent LHRH agonist properties when given during short-term and intermittent therapy, however, when administered in a continuous, nonpulsatile manner, LHRH analogs induce inhibition of gonadotropin secretion and suppression of testicular steroidogenesis.

Related product monographs

Title Information Source Document Type  
CAMCEVI Prolonged-release suspension for injection European Medicines Agency (EU) MPI, EU: SmPC
LECTRUM Powder for suspension for injection Marketing Authorisation Holder MPI, EU: SmPC
LUCRIN Depot Solution for injection Health Products Regulatory Authority (ZA) MPI, Generic
LUPRON DEPOT Powder for solution for injection FDA, National Drug Code (US) MPI, US: SPL/PLR
LUTRATE DEPOT Powder and solvent for prolonged-release suspension for injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
PROSTAP 3 DCS Powder and solvent for suspension for injection in pre-filled syringe Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Medicines in this ATC group

United States (US)

Australia (AU)

Brazil (BR)

Croatia (HR)

Cyprus (CY)

Estonia (EE)

Finland (FI)

France (FR)

Hong Kong (HK)

Israel (IL)

Lithuania (LT)

Malta (MT)

Mexico (MX)

Netherlands (NL)

New Zealand (NZ)

Singapore (SG)

South Africa (ZA)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.