The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
1
|
N | Nervous system | |
2
|
N03 | Antiepileptics | |
3
|
N03A | Antiepileptics | |
4
|
N03AF | Carboxamide derivatives |
| Code | Title | |
|---|---|---|
| N03AF01 | Carbamazepine | |
| N03AF02 | Oxcarbazepine | |
| N03AF03 | Rufinamide | |
| N03AF04 | Eslicarbazepine |
| Active Ingredient |
|---|
|
Carbamazepine is a derivative of dibenzazepine. It belongs to the pharmaceutical class of antiepileptic, neurotropic and psychotropic drugs. Carbamazepine helps control the transmission of messages from the brain to the muscles. |
|
Eslicarbazepine and its metabolites stabilise the inactivated state of voltage-gated sodium channels, precluding their return to the activated state and thereby preventing repetitive neuronal firing. Therefore eslicarbazepine is indicated as adjunctive therapy in adults with partial-onset seizures with or without secondary generalisation. |
|
The pharmacological activity of oxcarbazepine is primarily exerted through the metabolite (MHD). The mechanism of action of oxcarbazepine and MHD is thought to be mainly based on the blockade of voltage-sensitive sodium channels. |
|
Rufinamide is an anticonvulsant medication. Rufinamide modulates the activity of sodium channels, prolonging their inactive state. |
| Document | Type | Information Source | |
|---|---|---|---|
| APTIOM Tablet | MPI, US: SPL/PLR | FDA, National Drug Code (US) | |
| BANZEL Film-coated tablet / Oral suspension | MPI, US: SPL/PLR | FDA, National Drug Code (US) | |
| INOVELON Film-coated tablet | MPI, EU: SmPC | European Medicines Agency (EU) | |
| STORILAT Tablet | MPI, EU: SmPC | Υπουργείο Υγείας (CY) | |
| TAVER Tablet | MPI, EU: SmPC | Υπουργείο Υγείας (CY) | |
| Tegretol Tablets 100mg, 200mg, 400mg | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| TRILEPTAL Film-coated tablet | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| ZEBINIX Tablet | MPI, EU: SmPC | European Medicines Agency (EU) |