ATC Group: N03AF Carboxamide derivatives

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of N03AF in the ATC hierarchy

Level Code Title
1 N Nervous system
2 N03 Antiepileptics
3 N03A Antiepileptics
4 N03AF Carboxamide derivatives

Group N03AF contents

Code Title
N03AF01 Carbamazepine
N03AF02 Oxcarbazepine
N03AF03 Rufinamide
N03AF04 Eslicarbazepine

Active ingredients in N03AF

Active Ingredient Description
Carbamazepine

Carbamazepine is a derivative of dibenzazepine. It belongs to the pharmaceutical class of antiepileptic, neurotropic and psychotropic drugs. Carbamazepine helps control the transmission of messages from the brain to the muscles.

Eslicarbazepine

Eslicarbazepine and its metabolites stabilise the inactivated state of voltage-gated sodium channels, precluding their return to the activated state and thereby preventing repetitive neuronal firing. Therefore eslicarbazepine is indicated as adjunctive therapy in adults with partial-onset seizures with or without secondary generalisation.

Oxcarbazepine

The pharmacological activity of oxcarbazepine is primarily exerted through the metabolite (MHD). The mechanism of action of oxcarbazepine and MHD is thought to be mainly based on the blockade of voltage-sensitive sodium channels.

Rufinamide

Rufinamide is an anticonvulsant medication. Rufinamide modulates the activity of sodium channels, prolonging their inactive state.

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