ATC Group: N05AD Butyrophenone derivatives

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of N05AD in the ATC hierarchy

Level Code Title
1 N Nervous system
2 N05 Psycholeptics
3 N05A Antipsychotics
4 N05AD Butyrophenone derivatives

Group N05AD contents

Code Title
N05AD01 Haloperidol
N05AD02 Trifluperidol
N05AD03 Melperone
N05AD04 Moperone
N05AD05 Pipamperone
N05AD06 Bromperidol
N05AD07 Benperidol
N05AD08 Droperidol
N05AD09 Fluanisone
N05AD10

Active ingredients in N05AD

Active Ingredient

Benperidol is a strong dopamine receptor antagonist with weaker serotonin receptor antagonism. In high doses, it has antihistaminergic and alpha-adrenergic properties. It possesses minimal anticholinergic properties. Benperidol is a typical antipsychotic primarily used to treat hypersexuality syndromes and can be used to treat schizophrenia.

Droperidol is a butyrophenone neuroleptic. Its pharmacologic profile is characterised mainly by dopamine-blocking and weak α1-adrenolytic effects. Droperidol is devoid of anticholinergic and antihistaminic activity.

Haloperidol is an antipsychotic belonging to the butyrophenones group. It is a potent central dopamine type 2 receptor antagonist, and at recommended doses, has low alpha-1 antiadrenergic activity and no antihistaminergic or anticholinergic activity.

Related product monographs

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 ANQUIL Tablet MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)
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 HALOXEN Tablet MPI, EU: SmPC Υπουργείο Υγείας (CY)
 SERENACE Tablet MPI, EU: SmPC Health Products Regulatory Authority (IE)
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