The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.
| Level | Code | Title | |
|---|---|---|---|
1
|
N | Nervous system | |
2
|
N06 | Psychoanaleptics | |
3
|
N06A | Antidepressants | |
4
|
N06AF | Monoamine oxidase inhibitors, non-selective |
| Code | Title | |
|---|---|---|
| N06AF01 | Isocarboxazid | |
| N06AF02 | Nialamide | |
| N06AF03 | Phenelzine | |
| N06AF04 | Tranylcypromine | |
| N06AF05 | Iproniazide | |
| N06AF06 | Iproclozide |
| Active Ingredient |
|---|
|
|
|
Isocarboxazid is a monoamine oxidase inhibitor, effective in small doses. Its antidepressant action is thought to be related to its effect on physiological amines such as serotonin and noradrenaline, and this effect is cumulative and persistent. |
|
Phenelzine is an irreversible non-selective inhibitor of monoamine oxidase. Although the exact mechanism of action has not been determined, it appears that the irreversible, nonselective inhibition of MAO by phenelzine relieves depressive symptoms by causing an increase in the levels of serotonin, norepinephrine, and dopamine in the neuron. Phenelzine is used for the treatment of major depressive disorder. Has also been used with some success in the management of bulimia nervosa. |
| Document | Type | Information Source | |
|---|---|---|---|
| NARDIL Film coated tablet | MPI, EU: SmPC | Medicines & Healthcare Products Regulatory Agency (GB) | |
| PARNATE Film-coated tablet | MPI, US: SPL/PLR | FDA, National Drug Code (US) |