ATC Group: P02CA Benzimidazole derivatives

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of P02CA in the ATC hierarchy

Level Code Title
1 P Antiparasitic products, insecticides and repellents
2 P02 Anthelmintics
3 P02C Antinematodal agents
4 P02CA Benzimidazole derivatives

Group P02CA contents

Code Title
P02CA01 Mebendazole
P02CA02 Tiabendazole
P02CA03 Albendazole
P02CA04 Ciclobendazole
P02CA05 Flubendazole
P02CA06 Fenbendazole
P02CA51 Mebendazole, combinations

Active ingredients in P02CA

Active Ingredient Description
Albendazole

Albendazole causes degenerative alterations in the tegument and intestinal cells of the worm by binding to the colchicine-sensitive site of tubulin, thus inhibiting its polymerization or assembly into microtubules.

Flubendazole
Mebendazole

In vitro and in vivo work suggests that mebendazole blocks the uptake of glucose by adult and larval forms of helminths, in a selective and irreversible manner. Inhibition of glucose uptake appears to lead to endogenous depletion of glycogen stores within the helminth. Lack of glycogen leads to decreased formation of ATP and ultrastructural changes in the cells.

Tiabendazole

Related product monographs

Title Information Source Document Type  
ALBENZA Film-coated tablet FDA, National Drug Code (US) MPI, US: SPL/PLR
VERMOX Tablet Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC