ATC Group: R05CB13 Dornase alfa (desoxyribonuclease)

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of R05CB13 in the ATC hierarchy

Level Code Title
1 R Respiratory system
2 R05 Cough and cold preparations
3 R05C Expectorants, excl. combinations with cough suppressants
4 R05CB Mucolytics
5 R05CB13 Dornase alfa (desoxyribonuclease)

Defined daily dose

The DDD is the assumed average maintenance dose per day for a drug used for its main indication in adults. The DDD is a unit of measurement and does not necessarily reflect the recommended or Prescribed Daily Dose. Therapeutic doses for individual patients and patient groups will often differ from the DDD as they will be based on individual characteristics (such as age, weight, ethnic differences, type and severity of disease) and pharmacokinetic considerations.

Code Route Amount Notes
RESPIR Respiratory (Inhalation) 2.5 mg (solution)

Active ingredients in R05CB13

Active Ingredient

Recombinant human DNase is a genetically engineered version of a naturally occurring human enzyme which cleaves extracellular DNA. In vitro, dornase alfa hydrolyses DNA in sputum and greatly reduces the viscoelasticity of cystic fibrosis sputum.

Related product monographs

Document Type Information Source  
 PULMOZYME Nebuliser solution MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)

United States medicines

Medicines classified under this ATC code globally

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Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.