ATC Group: R07AB Respiratory stimulants

The World Health Organization's ATC classification organizes medical drugs based on therapeutic properties, chemical composition, and anatomy. It helps make essential medicines readily available globally and is widely used in the pharmaceutical industry.

Position of R07AB in the ATC hierarchy

Level Code Title
1 R Respiratory system
2 R07 Other respiratory system products
3 R07A Other respiratory system products
4 R07AB Respiratory stimulants

Group R07AB contents

Code Title
R07AB01 Doxapram
R07AB02 Nikethamide
R07AB03 Pentetrazol
R07AB04 Etamivan
R07AB05 Bemegride
R07AB06 Prethcamide
R07AB07 Almitrine
R07AB08 Dimefline
R07AB09 Mepixanox
R07AB52 Nikethamide, combinations
R07AB53 Pentetrazol, combinations

Active ingredients in R07AB

Active Ingredient Description
Almitrine

Almitrine is a diphenylmethylpiperazine derivative and respiratory stimulant that enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. It is used in the treatment of chronic obstructive pulmonary disease. It is also reported to have a potentially beneficial effect in treating the noctural oxygen desaturation without impairing the quality of sleep.

Bemegride

Bemegride is a CNS stimulant that is used to induce convulsions in experimental animals. It has also been used as a respiratory stimulant and in the treatment of barbiturate overdose. Bemegride is an antidote for barbiturate poisoning. Bemegride has being shown to have an antagonistic action on the GABAA receptor.

Doxapram

Doxapram is an analeptic agent (a stimulant of the central nervous system). Doxapram produces respiratory stimulation mediated through the peripheral carotid chemoreceptors. It is thought to stimulate the carotid body by inhibiting certain potassium channels. Used as temporary measure in hospitalized patients with acute respiratory insufficiency superimposed on chronic obstructive pulmonary disease.

Nikethamide

Related product monographs

Title Information Source Document Type  
DOPRAM Solution for injection FDA, National Drug Code (US) MPI, US: SPL/Old
DOPRAM Sterile solution for injection Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC
Doxapram Hydrochloride 2mg/ml Solution for Infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC