ACTEMRA

This brand name is authorized in Australia, Brazil, Canada, Ecuador, Hong Kong, Israel, Japan, New Zealand, Singapore, Tunisia, Turkey, United States, South Africa

Active ingredients

The drug ACTEMRA contains one active pharmaceutical ingredient (API):

1 Tocilizumab UNII I031V2H011 - TOCILIZUMAB

Tocilizumab binds specifically to both soluble and membrane-bound IL-6 receptors (sIL-6R and mIL-6R). IL-6 is involved in diverse physiological processes such as T-cell activation, induction of immunoglobulin secretion, induction of hepatic acute phase protein synthesis and stimulation of haemopoiesis. IL-6 has been implicated in the pathogenesis of diseases including inflammatory diseases, osteoporosis and neoplasia. Read about Tocilizumab

Medication package inserts

Below package inserts are available for further reading:

Title	Information Source	Document Type
ACTEMRA Solution for injection	FDA, National Drug Code (US)	MPI, US: SPL/PLR

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
L04AC07	Tocilizumab	L Antineoplastic and immunomodulating agents → L04 Immunosuppressants → L04A Immunosuppressants → L04AC Interleukin inhibitors
Discover more medicines within L04AC07

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: AU	Pharmaceutical Benefits Scheme	Identifier(s): 10056G, 10058J, 10060L, 10064Q, 10068X, 10071C, 10072D, 10073E, 10077J, 10078K, 10079L, 10081N, 10951J, 10954M, 11565Q, 11567T, 11720W, 11721X, 11722Y, 11725D, 11730J, 11734N, 11741Y, 11742B, 11743C, 11744D, 11748H, 11750K, 12083Y, 12084B, 12085C, 12086D, 12090H, 12094M, 12095N, 12099T, 12102Y, 12105D, 1419Q, 1423X, 1464C, 1476Q, 1481Y, 1482B, 9657G, 9658H, 9659J, 9671B, 9672C, 9673D
Country: BR	Câmara de Regulação do Mercado de Medicamentos	Identifier(s): 529208501150212, 529208502157210, 529215110026303, 529220090026707, 529220090026807
Country: CA	Health Products and Food Branch	Identifier(s): 02350092, 02350106, 02350114, 02424770, 02483327
Country: EC	Agencia Nacional de Regulación, Control y Vigilancia Sanitaria	Identifier(s): 202-MBE-0621, 28938-07-09
Country: HK	Department of Health Drug Office	Identifier(s): 59200, 59201, 59202, 63771
Country: IL	מִשְׂרַד הַבְּרִיאוּת	Identifier(s): 6415, 6416, 7772
Country: JP	医薬品医療機器総合機構	Identifier(s): 6399421A1020, 6399421A2026, 6399421A3022, 6399421G1022, 6399421G2029
Country: NZ	Medicines and Medical Devices Safety Authority	Identifier(s): 13435, 15812
Country: SG	Health Sciences Authority	Identifier(s): 13723P, 14837P
Country: TN	Direction de la Pharmacie et du Médicament	Identifier(s): 6993201H, 6993202H, 6993203H, 6993204H
Country: TR	İlaç ve Tıbbi Cihaz Kurumu	Identifier(s): 8699505762272, 8699505762289, 8699505762296, 8699505762302, 8699505762319, 8699505762326, 8699505952840
Country: US	FDA, National Drug Code	Identifier(s): 50242-135, 50242-136, 50242-137, 50242-138, 50242-143
Country: ZA	Health Products Regulatory Authority	Identifier(s): 43/30.1/0944, 43/30.1/0945, 43/30.1/0946, 49/30.1/0398