AKYNZEO

This brand name is authorized in Austria, Australia, Brazil, Canada, Ecuador, Estonia, Spain, Finland, France, Hong Kong, Croatia, Ireland, Israel, Lithuania, Netherlands, New Zealand, Poland, Romania, Singapore, Tunisia, United Kingdom, United States

Active ingredients

The drug AKYNZEO contains a combination of these active pharmaceutical ingredients (APIs):

1 Netupitant UNII 7732P08TIR - NETUPITANT

Netupitant is a selective antagonist of human substance P/neurokinin 1 (NK1) receptors. Delayed emesis has been associated with the activation of tachykinin family neurokinin 1 (NK1) receptors (broadly distributed in the central and peripheral nervous systems) by substance P. As shown in in vitro and in vivo studies, netupitant inhibits substance P mediated responses. Read about Netupitant

2 Palonosetron UNII 23310D4I19 - PALONOSETRON HYDROCHLORIDE

Palonosetron is a selective high-affinity receptor antagonist of the 5HT3 receptor. Read about Palonosetron

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code	Group title	Classification
A04AA55		A Alimentary tract and metabolism → A04 Antiemetics and antinauseants → A04A Antiemetics and antinauseants → A04AA Serotonin (5HT3) antagonists
Discover more medicines within A04AA55

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country	Identification scheme	Identifier(s)
Country: AU	Pharmaceutical Benefits Scheme	Identifier(s): 10714X, 10731T
Country: BR	Câmara de Regulação do Mercado de Medicamentos	Identifier(s): 556718050001902
Country: CA	Health Products and Food Branch	Identifier(s): 02468735
Country: EC	Agencia Nacional de Regulación, Control y Vigilancia Sanitaria	Identifier(s): 4768-MEE-0719
Country: EE	Ravimiamet	Identifier(s): 1686809, 1780129, 1814172, 1865235
Country: ES	Centro de información online de medicamentos de la AEMPS	Identifier(s): 1151001001
Country: FI	Lääkealan turvallisuus- ja kehittämiskeskus	Identifier(s): 376235
Country: FR	Base de données publique des médicaments	Identifier(s): 67693946
Country: GB	Medicines & Healthcare Products Regulatory Agency	Identifier(s): 307909
Country: HK	Department of Health Drug Office	Identifier(s): 65260
Country: IL	מִשְׂרַד הַבְּרִיאוּת	Identifier(s): 7798, 8966
Country: LT	Valstybinė vaistų kontrolės tarnyba	Identifier(s): 1076759, 1085765, 1089568
Country: NL	Z-Index G-Standaard, PRK	Identifier(s): 139696
Country: NZ	Medicines and Medical Devices Safety Authority	Identifier(s): 17936
Country: PL	Rejestru Produktów Leczniczych	Identifier(s): 100347479, 100433233
Country: RO	Agenția Națională a Medicamentului și a Dispozitivelor Medicale	Identifier(s): W62207001
Country: SG	Health Sciences Authority	Identifier(s): 15031P
Country: TN	Direction de la Pharmacie et du Médicament	Identifier(s): 4843011
Country: US	FDA, National Drug Code	Identifier(s): 69639-101, 69639-102, 69639-105