Palonosetron

Chemical formula: C₁₉H₂₄N₂O  Molecular mass: 296.414 g/mol  PubChem compound: 6337614

Active ingredient description

Palonosetron is a selective high-affinity receptor antagonist of the 5HT3 receptor.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
A04AA05 Palonosetron A Alimentary tract and metabolism → A04 Antiemetics and antinauseants → A04A Antiemetics and antinauseants → A04AA Serotonin (5HT3) antagonists
Discover more medicines within A04AA05

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
ALOXI Soft capsule European Medicines Agency (EU) MPI, EU: SmPC
ALOXI Solution for injection European Medicines Agency (EU) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 135729-56-5
DrugBank Drug: DB00377
KEGG Drug: D07175
PubChem Compound: 6337614
RxNorm Ingredient: 70561
SNOMED-CT Concept: 404852008
Palonosetron (substance)
UNII Identifier: 5D06587D6R
PALONOSETRON

Medicines

Palonosetron is an active ingredient of these brands:

United States (US)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Australia (AU)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Austria (AT)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Brazil (BR)

  • ONICIT as PALONOSETRON HYDROCHLORIDE
  • PALOCYT as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Canada (CA)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Croatia (HR)

  • FERANT as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Cyprus (CY)

Ecuador (EC)

  • PALOHALT as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Estonia (EE)

  • ALOXI as PALONOSETRON HYDROCHLORIDE
  • FERANT as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Finland (FI)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

France (FR)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Hong Kong (HK)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Ireland (IE)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Israel (IL)

  • PALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Japan (JP)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

Lithuania (LT)

  • ALOXI as PALONOSETRON HYDROCHLORIDE
  • FERANT as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Malta (MT)

  • FERANT as PALONOSETRON HYDROCHLORIDE

Mexico (MX)

  • ONICIT as PALONOSETRON HYDROCHLORIDE

Netherlands (NL)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

New Zealand (NZ)

  • ALOXI as PALONOSETRON HYDROCHLORIDE
  • ONICIT as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Poland (PL)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Romania (RO)

  • ALOXI as PALONOSETRON HYDROCHLORIDE
  • FERANT as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Singapore (SG)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

South Africa (ZA)

  • BEVATIVA as PALONOSETRON HYDROCHLORIDE
  • NOCIPAL as PALONOSETRON HYDROCHLORIDE
  • ONICIT as PALONOSETRON HYDROCHLORIDE
  • PALCITA as PALONOSETRON HYDROCHLORIDE
  • PALTON as PALONOSETRON HYDROCHLORIDE

Spain (ES)

  • ALOXI as PALONOSETRON HYDROCHLORIDE
  • FERANT as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Tunisia (TN)

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Turkey (TR)

  • ALOXI as PALONOSETRON HYDROCHLORIDE
  • CINVEX as PALONOSETRON HYDROCHLORIDE
  • DEKOL
  • EMTRON as PALONOSETRON HYDROCHLORIDE
  • GENOLAX as PALONOSETRON HYDROCHLORIDE
  • LOTISA as PALONOSETRON HYDROCHLORIDE
  • PALODIN as PALONOSETRON HYDROCHLORIDE
  • PALOJECT as PALONOSETRON HYDROCHLORIDE
  • PALONDEM as PALONOSETRON HYDROCHLORIDE
  • PALONEX as PALONOSETRON HYDROCHLORIDE
  • PALOXITRON as PALONOSETRON HYDROCHLORIDE
  • PALSEL as PALONOSETRON HYDROCHLORIDE
  • PELATOS as PALONOSETRON HYDROCHLORIDE
  • PLARON as PALONOSETRON HYDROCHLORIDE
  • VOMISET as PALONOSETRON HYDROCHLORIDE
  • VONAXI as PALONOSETRON HYDROCHLORIDE
  • VOTRON as PALONOSETRON HYDROCHLORIDE
  • ZIAXE as PALONOSETRON HYDROCHLORIDE

United Kingdom (UK)

  • ALOXI as PALONOSETRON HYDROCHLORIDE

  • (combination) AKYNZEO as PALONOSETRON HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

© All content on this website, including data entry, data processing, decision support tools, "RxReasoner" logo and graphics, is the intellectual property of RxReasoner and is protected by copyright laws. Unauthorized reproduction or distribution of any part of this content without explicit written permission from RxReasoner is strictly prohibited. Any third-party content used on this site is acknowledged and utilized under fair use principles.