This brand name is authorized in Romania
The drug ARPARIAL contains a combination of these active pharmaceutical ingredients (APIs):
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1
Metoprolol
UNII GEB06NHM23 - METOPROLOL
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Metoprolol is a cardioselective beta-adrenergic blocking agent. It has a relatively greater blocking effect on beta1-receptors (ie those mediating adrenergic stimulation of heart rate and contractility and release of free fatty acids from fat stores) than on beta2-receptors, which are chiefly involved in broncho and vasodilation. |
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2
Ivabradine
UNII 3H48L0LPZQ - IVABRADINE
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Ivabradine is a pure heart rate lowering agent, acting by selective and specific inhibition of the cardiac pacemaker If current that controls the spontaneous diastolic depolarisation in the sinus node and regulates heart rate. The cardiac effects are specific to the sinus node with no effect on intra-atrial, atrioventricular or intraventricular conduction times, nor on myocardial contractility or ventricular repolarisation. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C07FX05 | C Cardiovascular system → C07 Beta blocking agents → C07F Beta blocking agents and other antihypertensives → C07FX Beta blocking agents, other combinations | |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: RO | Agenția Națională a Medicamentului și a Dispozitivelor Medicale | Identifier(s): W61986001, W61986002, W61986003, W61986004, W61986005, W61987001, W61987002, W61987003, W61987004, W61987005, W61988001, W61988002, W61988003, W61988004, W61988005, W61989001, W61989002, W61989003, W61989004, W61989005 |
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