This brand name is authorized in United States
The drug AZEDRA contains one active pharmaceutical ingredient (API):
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1
Iobenguane ¹³¹I
UNII Q461L7AK4R - IOBENGUANE I-131
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Iobenguane is similar in structure to the neurotransmitter norepinephrine (NE) and is subject to the same uptake and accumulation pathways as NE. Pheochromocytoma and paraganglioma (PPGL) are tumors of neural crest origin that express high levels of the NE transporter on their cell surfaces. Following intravenous administration, iobenguane ¹³¹I is taken up and accumulates within pheochromocytoma and paraganglioma cells, and radiation resulting from radioactive decay of ¹³¹I causes cell death and tumor necrosis. |
Below package inserts are available for further reading:
| Title | Information Source | Document Type | |
|---|---|---|---|
| AZEDRA Solution for injection | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: US | FDA, National Drug Code | Identifier(s): 71258-015 |
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