This brand name is authorized in Germany, France, Italy, Turkey, South Africa
The drug CIBADREX contains a combination of these active pharmaceutical ingredients (APIs):
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1
Benazepril
UNII N1SN99T69T - BENAZEPRIL HYDROCHLORIDE
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Benazepril is a prodrug which, after hydrolysis to the active substance benazeprilat, inhibits the angiotensin-converting enzyme (ACE) and so blocks the conversion of angiotensin I to angiotensin II. This reduces all the effects mediated by angiotensin II – i.e. vasoconstriction and production of aldosterone, which promotes the reabsorption of sodium and water in the renal tubules – and elevates cardiac output. |
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2
Hydrochlorothiazide
UNII 0J48LPH2TH - HYDROCHLOROTHIAZIDE
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Hydrochlorothiazide is a diuretic with antihypertensive properties. It acts by inhibiting the renal tubular re-absorption of sodium and chloride ions, which are excreted with an accompanying volume of water. Potassium excretion is also promoted. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C09AA07 | Benazepril | C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09A ACE inhibitors, plain → C09AA ACE inhibitors, plain |
| C09BA07 | Benazepril and diuretics | C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09B ACE inhibitors, combinations → C09BA ACE inhibitors and diuretics |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: DE | Bundesinstitut für Arzneimittel und Medizinprodukte | Identifier(s): 04855477 |
| Country: FR | Base de données publique des médicaments | Identifier(s): 61591226 |
| Country: IT | Agenzia del Farmaco | Identifier(s): 028037024 |
| Country: TR | İlaç ve Tıbbi Cihaz Kurumu | Identifier(s): 8698856090072, 8698856090089 |
| Country: ZA | Health Products Regulatory Authority | Identifier(s): 28/7.1.3/0120, 28/7.1.3/0121, 28/7.1.3/0122, 28/7.1.3/0123 |
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