This brand name is authorized in Brazil, Ecuador, France, Mexico
The drug CLIMENE contains a combination of these active pharmaceutical ingredients (APIs):
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1
Estradiol
UNII OKG364O896 - ESTRADIOL VALERATE
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Estradiol, is chemically and biologically identical to endogenous human estradiol. It substitutes for the loss of oestrogen production in menopausal women, and alleviates menopausal symptoms. Oestrogens prevent bone loss following menopause or ovariectomy. |
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2
Cyproterone
UNII 4KM2BN5JHF - CYPROTERONE ACETATE
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Cyproterone acetate acts as an antiandrogen by blocking androgen receptors. It also has progestogenic activity, which exerts a negative feedback effect on hypothalamic receptors, so leading to a reduction in gonadotrophin release, and hence to diminished production of testicular androgens. Sexual drive and potency are reduced and gonadal function is inhibited. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| G03HB01 | Cyproterone and estrogen | G Genito urinary system and sex hormones → G03 Sex hormones and modulators of the genital system → G03H Antiandrogens → G03HB Antiandrogens and estrogens |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: BR | Câmara de Regulação do Mercado de Medicamentos | Identifier(s): 538912050012213 |
| Country: EC | Agencia Nacional de Regulación, Control y Vigilancia Sanitaria | Identifier(s): 26.892-02-06 |
| Country: FR | Base de données publique des médicaments | Identifier(s): 61847608 |
| Country: MX | Comisión Federal para la Protección contra Riesgos Sanitarios | Identifier(s): 187M92 |
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