Chemical formula: C₁₈H₂₄O₂ Molecular mass: 272.382 g/mol PubChem compound: 5757
Estradiol, is chemically and biologically identical to endogenous human estradiol. It substitutes for the loss of oestrogen production in menopausal women, and alleviates menopausal symptoms. Oestrogens prevent bone loss following menopause or ovariectomy.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| G03CA03 | Estradiol | G Genito urinary system and sex hormones → G03 Sex hormones and modulators of the genital system → G03C Estrogens → G03CA Natural and semisynthetic estrogens, plain |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| ESTRACE Tablet | FDA, National Drug Code (US) | MPI, US: SPL/Old | |
| ESTRACE Cream | FDA, National Drug Code (US) | MPI, US: SPL/Old | |
| CLIMARA Patch | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| ZUMENON Film-coated tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| ESTRING Vaginal delivery system | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| DIVIGEL Gel | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| VAGIRUX Vaginal tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| ESTRADOT Transdermal patch | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| ESTROGEL Gel | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Estradiol is an active ingredient of these brands:
United States (US)
Australia (AU)Austria (AT)
Brazil (BR)
Canada (CA)Croatia (HR)
Cyprus (CY)Ecuador (EC)
Estonia (EE)
Finland (FI)
France (FR)
Germany (DE)
Hong Kong (HK)
Ireland (IE)
Israel (IL)
Italy (IT)
Japan (JP)
Lithuania (LT)
Malta (MT)
Mexico (MX)
Netherlands (NL)
New Zealand (NZ)
Poland (PL)
Romania (RO)Singapore (SG)
South Africa (ZA)
Spain (ES)
Tunisia (TN)Turkey (TR)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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