DEMSER

This brand name is authorized in Japan, United Kingdom, United States

Active ingredients

The drug DEMSER contains one active pharmaceutical ingredient (API):

1 Metirosine
UNII DOQ0J0TPF7 - METYROSINE

Metirosine inhibits tyrosine hydroxylase, which catalyzes the first transformation in catecholamine biosynthesis, i.e., the conversion of tyrosine to dihydroxyphenylalanine (DOPA). Because the first step is also the rate-limiting step, blockade of tyrosine hydroxylase activity results in decreased endogenous levels of catecholamines, usually measured as decreased urinary excretion of catecholamines and their metabolites.

Read about Metirosine

Medication package inserts

Below package inserts are available for further reading:

Title Information Source Document Type  
DEMSER Capsule FDA, National Drug Code (US) MPI, US: SPL/Old

Medicine classification

This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:

ATC code Group title Classification
C02KB01 Metirosine C Cardiovascular system → C02 Antihypertensives → C02K Other antihypertensives → C02KB Tyrosine hydroxylase inhibitors
Discover more medicines within C02KB01

Authorization and marketing

This drug has been assigned below unique identifiers within the countries it is being marketed:

Country Identification scheme Identifier(s)
Country: GB Medicines & Healthcare Products Regulatory Agency Identifier(s): 199323
Country: JP 医薬品医療機器総合機構 Identifier(s): 2190038M1024
Country: US FDA, National Drug Code Identifier(s): 25010-305

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