This brand name is authorized in South Africa
The drug DEZRETIC contains a combination of these active pharmaceutical ingredients (APIs):
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1
Amiloride
UNII FZJ37245UC - AMILORIDE HYDROCHLORIDE
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Amiloride has mild diuretic and anti-hypertensive activity. It acts primarily in the distal tubule and does not require aldosterone for its action. Amiloride is a mild natriuretic which does not initiate a concomitant decrease in potassium levels. |
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2
Hydrochlorothiazide
UNII 0J48LPH2TH - HYDROCHLOROTHIAZIDE
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Hydrochlorothiazide is a diuretic with antihypertensive properties. It acts by inhibiting the renal tubular re-absorption of sodium and chloride ions, which are excreted with an accompanying volume of water. Potassium excretion is also promoted. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C03EA01 | Hydrochlorothiazide and potassium-sparing agents | C Cardiovascular system → C03 Diuretics → C03E Diuretics and potassium-sparing agents in combination → C03EA Low-ceiling diuretics and potassium-sparing agents |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: ZA | Health Products Regulatory Authority | Identifier(s): 28/18.1/0684 |
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