Chemical formula: C₆H₈ClN₇O Molecular mass: 229.627 g/mol PubChem compound: 16231
Amiloride has mild diuretic and anti-hypertensive activity. It acts primarily in the distal tubule and does not require aldosterone for its action. Amiloride is a mild natriuretic which does not initiate a concomitant decrease in potassium levels.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C03DB01 | Amiloride | C Cardiovascular system → C03 Diuretics → C03D Potassium-sparing agents → C03DB Other potassium-sparing agents |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| AMILORIDE ROSEMONT Oral solution | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Amiloride is an active ingredient of these brands:
Australia (AU)
Austria (AT)
Brazil (BR)Canada (CA)Cyprus (CY)Ecuador (EC)
Estonia (EE)
Finland (FI)France (FR)Germany (DE)Hong Kong (HK)
Ireland (IE)
Israel (IL)
Malta (MT)
Mexico (MX)
New Zealand (NZ)Nigeria (NG)Poland (PL)
South Africa (ZA)
Spain (ES)Tunisia (TN)
Turkey (TR)
United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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