This brand name is authorized in Hong Kong, Singapore
The drug DHASEDYL contains a combination of these active pharmaceutical ingredients (APIs):
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1
Demorphan
UNII W9F1OD5N5J - DEUDEXTROMETHORPHAN HYDROBROMIDE
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Dextromethorphan is a non-opioid antitussive drug. The major metabolite of dextromethorphan, dextrorphan, binds with high affinity to σ-receptors to produce its antitussive activity without exhibiting the classic opiate effects that occur from binding into μ- and δ-receptors. In larger than therapeutic doses, dextrorphan is also an antagonist of N-methyl-D-aspartate (NMDA) receptors. |
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2
Ephedrine
UNII NLJ6390P1Z - EPHEDRINE HYDROCHLORIDE
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Ephedrine is a sympathomimetic amine acting directly on the alpha and beta receptors and indirectly by increasing the release of noradrenaline by the sympathetic nerve endings. As with any sympathomimetic agent, ephedrine stimulates the central nervous system, the cardiovascular system, the respiratory system, and the sphincters of the digestive and urinary systems. |
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3
Promethazine
UNII R61ZEH7I1I - PROMETHAZINE HYDROCHLORIDE
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Promethazine is a potent, long acting, antihistamine with additional anti-emetic central sedative and anti-cholinergic properties. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| R05DA20 | Combinations | R Respiratory system → R05 Cough and cold preparations → R05D Cough suppressants, excl. combinations with expectorants → R05DA Opium alkaloids and derivatives |
| R06AD52 | Promethazine, combinations | R Respiratory system → R06 Antihistamines for systemic use → R06A Antihistamines for systemic use → R06AD Phenothiazine derivatives |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: HK | Department of Health Drug Office | Identifier(s): 50865, 55689 |
| Country: SG | Health Sciences Authority | Identifier(s): 06928P, 08748P |
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