This brand name is authorized in Canada
The drug DIMETAPP EXTRA STRENGTH DM COUGH & COLD contains a combination of these active pharmaceutical ingredients (APIs):
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1
Brompheniramine
UNII IXA7C9ZN03 - BROMPHENIRAMINE MALEATE
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2
Demorphan
UNII 9D2RTI9KYH - DEXTROMETHORPHAN HYDROBROMIDE
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Dextromethorphan is a non-opioid antitussive drug. The major metabolite of dextromethorphan, dextrorphan, binds with high affinity to σ-receptors to produce its antitussive activity without exhibiting the classic opiate effects that occur from binding into μ- and δ-receptors. In larger than therapeutic doses, dextrorphan is also an antagonist of N-methyl-D-aspartate (NMDA) receptors. |
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3
Phenylephrine
UNII 04JA59TNSJ - PHENYLEPHRINE HYDROCHLORIDE
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Phenylephrine is a sympathomimetic agent with mainly direct effects on adrenergic receptors. It has predominantly alpha adrenergic activity and is without stimulating effects on the central nervous system. The sympathomimetic effect of phenylephrine produces vasoconstriction which in turn relieves nasal congestion. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| R05DA20 | Combinations | R Respiratory system → R05 Cough and cold preparations → R05D Cough suppressants, excl. combinations with expectorants → R05DA Opium alkaloids and derivatives |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: CA | Health Products and Food Branch | Identifier(s): 02245076 |
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