This brand name is authorized in Estonia, Lithuania, Poland
The drug DIRONORM contains a combination of these active pharmaceutical ingredients (APIs):
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1
Lisinopril
UNII E7199S1YWR - LISINOPRIL
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Lisinopril is a peptidyl dipeptidase inhibitor. It inhibits the angiotensin-converting enzyme (ACE) that catalyses the conversion of angiotensin I to the vasoconstrictor peptide, angiotensin II. Angiotensin II also stimulates aldosterone secretion by the adrenal cortex. Inhibition of ACE results in decreased concentrations of angiotensin II which results in decreased vasopressor activity and reduced aldosterone secretion. |
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2
Amlodipine
UNII 864V2Q084H - AMLODIPINE BESYLATE
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Amlodipine is a calcium ion influx inhibitor of the dihydropyridine group (slow channel blocker or calcium ion antagonist) and inhibits the transmembrane influx of calcium ions into cardiac and vascular smooth muscle. |
This drug has been classified in the anatomical therapeutic chemical (ATC) classification system as follows:
| ATC code | Group title | Classification |
|---|---|---|
| C09BB03 | Lisinopril and amlodipine | C Cardiovascular system → C09 Agents acting on the renin-angiotensin system → C09B ACE inhibitors, combinations → C09BB ACE inhibitors and calcium channel blockers |
This drug has been assigned below unique identifiers within the countries it is being marketed:
| Country | Identification scheme | Identifier(s) |
|---|---|---|
| Country: EE | Ravimiamet | Identifier(s): 1300598, 1501456, 1501467, 1527645, 1588967, 1588978, 1588989, 1588990, 1589003, 1589014, 1589025, 1589036 |
| Country: LT | Valstybinė vaistų kontrolės tarnyba | Identifier(s): 1005464, 1005630, 1052561, 1057251, 1065400, 1080181, 1080798 |
| Country: PL | Rejestru Produktów Leczniczych | Identifier(s): 100209814, 100222039, 100278531 |
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